G protein-coupled receptors (GPCRs) are the largest group of cell surface receptors in
humans that signal in response to diverse inputs and regulate a plethora of cellular …

Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …

As the immune-competent cells of the brain, microglia play an increasingly important role in
maintaining normal brain function. They invade the brain early in development, transform …

Autism spectrum disorder (ASD) is a common neurodevelopmental disorder with onset in
childhood. The mechanisms underlying ASD are unclear. In recent years, the role of …

Autism spectrum disorder (ASD) is a complex heterogeneous neurodevelopmental disorder
with a complex pathogenesis. Many studies over the last four decades have recognized …

Background The three-dimensional (3D) architecture of the genome has a highly ordered
and hierarchical nature, which influences the regulation of essential nuclear processes at …

As the major excitatory neurotransmitter in the mammalian central nervous system,
glutamate plays a key role in many central pathologies, including gliomas, psychiatric …

Background Although the precise pathophysiologies underlying autism spectrum disorder
(ASD) has not yet been fully clarified, growing evidence supports the involvement of …

Ongoing neuroinflammation may contribute to symptoms of autism spectrum disorder (ASD)
in at least a portion of affected individuals. Mesenchymal stromal cells (MSCs) have …

Objective To evaluate whether umbilical cord blood (CB) infusion is safe and associated
with improved social and communication abilities in children with autism spectrum disorder …