Rotavirus infections are a leading cause of severe, dehydrating gastroenteritis in children< 5
years of age. Despite the global introduction of vaccinations for rotavirus over a decade ago …

Viral infection is controlled by host innate immune cells that express specialized receptors
for viral components. Engagement of these pattern recognition receptors triggers a series of …

Rotavirus, a leading cause of severe gastroenteritis and diarrhoea in young children,
accounts for around 215,000 deaths annually worldwide. Rotavirus specifically infects the …

Recent advances of rotavirus (RV) basic and applied research are reviewed. They consist of
determination of the RV particle structure and functions of structural proteins, classification …

Outbreaks of severe virus infections with the potential to cause global pandemics are
increasing. In many instances these outbreaks have been newly emerging (SARS …

The nuclear factor-κB (NF-κB) family of transcription factors plays a central part in the host
response to infection by microbial pathogens, by orchestrating the innate and acquired host …

Rotaviruses (RVs) are highly important pathogens that cause severe diarrhea among infants
and young children worldwide. The understanding of the molecular mechanisms underlying …

Rotaviruses cause life-threatening gastroenteritis in children worldwide; the enormous
disease burden has focused efforts to develop vaccines and led to the discovery of novel …

Both melatonin and proteasome inhibitors upregulate antioxidant enzymes including
superoxide dismutase (SOD), glutathione peroxidase (GP), hemoxygenase 1 (HO-1), and …

The intestinal epithelial barrier is patrolled by resident intraepithelial lymphocytes (IELs) that
are involved in host defence against pathogens, wound repair and homeostatic interactions …