FKBP5 inhibitors modulate alcohol drinking and trauma-related behaviors in a model of comorbid post-traumatic stress and alcohol use disorder
Post-traumatic stress disorder (PTSD) leads to enhanced alcohol drinking and development
of alcohol use disorder (AUD). Identifying shared neural mechanisms might help discover …
of alcohol use disorder (AUD). Identifying shared neural mechanisms might help discover …
[HTML][HTML] Alcohol-endocannabinoid interactions: implications for addiction-related behavioral processes
A Serrano, LA Natividad - Alcohol research: current reviews, 2022 - ncbi.nlm.nih.gov
PURPOSE The endogenous cannabinoid system is involved in several physiological
functions in the central nervous system including the modulation of brain reward circuitry …
functions in the central nervous system including the modulation of brain reward circuitry …
[HTML][HTML] Excessive alcohol intake produces persistent mechanical allodynia and dysregulates the endocannabinoid system in the lumbar dorsal root ganglia of …
Epidemiological data indicate a strong association between alcohol use disorder (AUD) and
neuropathic pain. Genetically-selected Marchigian Sardinian alcohol-preferring (msP) rats …
neuropathic pain. Genetically-selected Marchigian Sardinian alcohol-preferring (msP) rats …
[HTML][HTML] Glucocorticoid receptors regulate central amygdala GABAergic synapses in Marchigian-Sardinian alcohol-preferring rats
Impairments in the function of the hypothalamic-pituitary-adrenal (HPA) axis and enhanced
glucocorticoid receptor (GR) activity in the central amygdala (CeA) are critical mechanisms …
glucocorticoid receptor (GR) activity in the central amygdala (CeA) are critical mechanisms …
Sexually dimorphic effects of monoacylglycerol lipase inhibitor MJN110 on stress‐related behaviour and drinking in Marchigian Sardinian alcohol‐preferring rats
Abstract Background and Purpose The endocannabinoid (eCB) system plays an important
homeostatic role in the regulation of stress circuits and has emerged as a therapeutic target …
homeostatic role in the regulation of stress circuits and has emerged as a therapeutic target …
[HTML][HTML] Early social isolation differentially affects the glucocorticoid receptor system and alcohol-seeking behavior in male and female Marchigian Sardinian alcohol …
F Benvenuti, S De Carlo, L Rullo, L Caffino… - Neurobiology of …, 2024 - Elsevier
Adverse early life experiences during postnatal development can evoke long-lasting
neurobiological changes in stress systems, thereby affecting subsequent behaviors …
neurobiological changes in stress systems, thereby affecting subsequent behaviors …
Effect of glucocorticoid receptor antagonism on alcohol self-administration in genetically-selected marchigian sardinian alcohol-preferring and non-preferring wistar …
F Benvenuti, N Cannella, S Stopponi… - International journal of …, 2021 - mdpi.com
Alcoholism is a chronically relapsing disorder characterized by high alcohol intake and a
negative emotional state during abstinence, which contributes to excessive drinking and …
negative emotional state during abstinence, which contributes to excessive drinking and …
Glucocorticoid receptor antagonist mifepristone does not alter innate anxiety-like behavior in genetically-selected marchigian sardinian (msP) rats
Marchigian Sardinian alcohol-preferring (msP) rats serve as a unique model of heightened
alcohol preference and anxiety disorders. Their innate enhanced stress and poor stress …
alcohol preference and anxiety disorders. Their innate enhanced stress and poor stress …
Sex differences and the lack of effects of chemogenetic manipulation of pro-opiomelanocortin (POMC) neurons on alcohol consumption in male and female mice
JM Leyrer-Jackson, LE Hood, MF Olive - Brain research, 2022 - Elsevier
The endogenous opioid system has been implicated in the rewarding and reinforcing effects
of alcohol. Pro-opiomelanocortin (POMC) neurons located within the arcuate nucleus of the …
of alcohol. Pro-opiomelanocortin (POMC) neurons located within the arcuate nucleus of the …
Impact of individual differences in the development of opioid dependence
V Lunerti - 2022 - tesidottorato.depositolegale.it
Opioid use disorder (OUD) is a chronic relapsing brain disease characterized by compulsion
to seek and take the drug despite adverse consequences that has recently risen epidemic …
to seek and take the drug despite adverse consequences that has recently risen epidemic …