Q-FADD: a mechanistic approach for modeling the accumulation of proteins at sites of DNA...

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Poly (ADP-ribose) polymerase 1 searches DNA via a 'monkey bar'mechanism

J Rudolph, J Mahadevan, P Dyer, K Luger - Elife, 2018 - elifesciences.org
Poly (ADP-ribose) polymerase 1 (PARP1) is both a first responder to DNA damage and a
chromatin architectural protein. How PARP1 rapidly finds DNA damage sites in the context …
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