Sialic acids are a family of negatively charged monosaccharides which are commonly
presented as the terminal residues in glycans of the glycoconjugates on eukaryotic cell …

Sialic acid (Sia), the acylated derivative of the nine-carbon sugar neuraminic acid, is a
terminal component of the oligosaccharide chains of many glycoproteins and glycolipids. In …

Inhibitors of human neuraminidase enzymes (NEU) are recognized as important tools for the
study of the biological functions of NEU and will be potent tools for elucidating the role of …

Gardnerella vaginalis is abundant in bacterial vaginosis (BV), a condition associated with
adverse reproductive health. Sialidase activity is a diagnostic feature of BV and is produced …

Sialic acids are important recognition sites in protein-and lipid-linked glycans of higher
organisms and of select bacteria and protozoa. They are also prominent in human milk …

Invasion of erythrocytes by Plasmodial merozoites is a composite process involving the
interplay of several proteins. Among them, the Plasmodium falciparum Cysteine-Rich …

Human neuraminidases (NEU) are associated with human diseases including cancer,
atherosclerosis, and diabetes. To obtain small molecule inhibitors as research tools for the …

Potent, cell-permeable, and subtype-selective sialyltransferase inhibitors represent an
attractive family of substances that can potentially be used for the clinical treatment of cancer …

Abstract Sialidases, or neuraminidases (EC 3.2. 1.18), belong to a class of glycosyl
hydrolases that release terminal N-acylneuraminate residues from the glycans of …

A dense glycocalix covers the surface of Trypanosoma cruzi, the agent of Chagas disease.
Sialic acid in the surface of the parasite plays an important role in the infectious process …