Redefining precision radiotherapy through liquid biopsy

DB McLaren, TJ Aitman - British Journal of Cancer, 2023 - nature.com
Precision radiotherapy refers to the ability to deliver radiation doses with sub-millimetre
accuracy. It does not however consider individual variation in tumour or normal tissue …

Cancer signature ensemble integrating cfDNA methylation, copy number, and fragmentation facilitates multi-cancer early detection

SY Kim, S Jeong, W Lee, Y Jeon, YJ Kim… - … & molecular medicine, 2023 - nature.com
Cell-free DNA (cfDNA) sequencing has demonstrated great potential for early cancer
detection. However, most large-scale studies have focused only on either targeted …

Use of circulating cell-free methylated dna to detect tissue damage

A Wellstein, ME McNamara - US Patent App. 18/291,113, 2024 - Google Patents
CDKIEBFIMCSCBB-UHFFFAOYSA-N 1-(6, 7-dimethoxy-3, 4-dihydro-1h-isoquinolin-2-yl)-3-
(1-methyl-2-phenylpyrrolo [2, 3-b] pyridin-3-yl) prop-2-en-1-one; hydrochloride Chemical …