It is puzzling that hydrogen-rich fatty acids are used only poorly as fuel in the brain. The long-
standing belief that a slow passage of fatty acids across the blood–brain barrier might be the …

Mitochondrial dysfunction is central to numerous diseases of oxidative stress. Changes in
mitochondrial DNA (MtDNA) content, often measured as mitochondrial genome to nuclear …

The association of hepatic mitochondrial function with insulin resistance and non-alcoholic
fatty liver (NAFL) or steatohepatitis (NASH) remains unclear. This study applied high …

The mammalian brain is one of the organs with the highest energy demands, and
mitochondria are key determinants of its functions. Here we show that the type-1 …

Mitochondrial glycerol-3-phosphate dehydrogenase (mGPDH) is not included in the
traditional textbook schemes of the respiratory chain, reflecting the fact that it is a non …

A considerable amount of knowledge has been produced during the last five years on the
bioenergetics of cancer cells, leading to a better understanding of the regulation of energy …

Mitochondria play a key role in energy metabolism in many tissues, including cardiac and
skeletal muscle, brain, liver, and adipose tissue. Three types of adipose depots can be …

The pathophysiology of type 2 diabetes mellitus (DM) is varied and complex. However, the
association of DM with obesity and inactivity indicates an important, and potentially …

Mitochondria form a dynamic network, and it remains unclear how the alternate
configurations interact with bioenergetics properties. The metabolic signals that link …

Epilepsy is considered one of the most common neurological disorders worldwide. Oxidative
stress produced by free radicals may play a role in the initiation and progression of epilepsy; …