Glutamatergic neurotransmission: A potential pharmacotherapeutic target for the treatment of cognitive disorders
P Chakraborty, A Dey, AV Gopalakrishnan… - Ageing Research …, 2023 - Elsevier
In the mammalian brain, glutamate is regarded to be the primary excitatory neurotransmitter
due to its widespread distribution and wide range of metabolic functions. Glutamate plays …
due to its widespread distribution and wide range of metabolic functions. Glutamate plays …
Therapeutic detoxification of quercetin for aflatoxin B1-related toxicity: Roles of oxidative stress, inflammation, and metabolic enzymes
Aflatoxins (AFTs), a type of mycotoxin mainly produced by Aspergillus parasiticus and
Aspergillus flavus, could be detected in food, feed, Chinese herbal medicine, grain crops …
Aspergillus flavus, could be detected in food, feed, Chinese herbal medicine, grain crops …
[HTML][HTML] Quercetin antagonizes the sedative effects of linalool, possibly through the GABAergic interaction pathway
Sedatives promote calmness or sleepiness during surgery or severely stressful events. In
addition, depression is a mental health issue that negatively affects emotional well-being. A …
addition, depression is a mental health issue that negatively affects emotional well-being. A …
Extra virgin coconut oil (Cocos nucifera L.) intake shows neurobehavioural and intestinal health effects in obesity-induced rats
MHA de Vasconcelos, RL Tavares… - Food & Function, 2023 - pubs.rsc.org
The present study aimed to evaluate the effect of E-VCO on the neurobehaviour and
intestinal health parameters of obesity-induced rats, focusing on food consumption, body …
intestinal health parameters of obesity-induced rats, focusing on food consumption, body …
Quercetin action on health and female reproduction in mammals
AV Sirotkin - Critical Reviews in Food Science and Nutrition, 2023 - Taylor & Francis
This paper reviews the current information concerning availability, metabolism of quercetin,
its effects on physiological processes and illnesses with focus on the effects, mechanisms of …
its effects on physiological processes and illnesses with focus on the effects, mechanisms of …
Quercetin Ameliorates Cognitive Impairment in Depression by Targeting HSP90 to Inhibit NLRP3 Inflammasome Activation
L Du, X Fan, Y Yang, S Wu, Y Liu - Molecular Neurobiology, 2024 - Springer
Cognitive dysfunction was a common symptom of major depressive disorder (MDD). In
previous studies, psychological stress leads to activation and proliferation of microglial cells …
previous studies, psychological stress leads to activation and proliferation of microglial cells …
Quercetin alleviates chronic unpredictable mild stress‐induced depression‐like behavior by inhibiting NMDAR1 with α2δ‐1 in rats
M Wang, X Wei, Y Jia, C Wang, X Wang… - CNS Neuroscience …, 2024 - Wiley Online Library
Background Depression is a serious mental disorder and the most prevalent cause of
disability and suicide worldwide. Chronic unpredictable mild stress (CUMS) can lead to a …
disability and suicide worldwide. Chronic unpredictable mild stress (CUMS) can lead to a …
Exploring the potential of Cytisus purgans as a source of bioactive molecules: In vitro pharmacological evaluation
Introduction Cytisus purgans is an uncommon species found in Algeria (Aures, Mahdids and
Lella Khadidja). In the current study, we present, to the best of our knowledge, the first …
Lella Khadidja). In the current study, we present, to the best of our knowledge, the first …
Integrated bioinformatics and network pharmacology identifying the mechanisms and molecular targets of Guipi Decoction for treatment of comorbidity with depression …
M Liu, G Fan, H Liu - Metabolic Brain Disease, 2024 - Springer
Background Guipi decoction (GPD) not only improves gastrointestinal (GI) function, but also
depressive mood. The bioinformatics study aimed to reveal potential crosstalk genes and …
depressive mood. The bioinformatics study aimed to reveal potential crosstalk genes and …