Wound healing: cellular mechanisms and pathological outcomes

HN Wilkinson, MJ Hardman - Open biology, 2020 - royalsocietypublishing.org
Wound healing is a complex, dynamic process supported by a myriad of cellular events that
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …

Bioactive materials promote wound healing through modulation of cell behaviors

R Li, K Liu, X Huang, D Li, J Ding, B Liu… - Advanced …, 2022 - Wiley Online Library
Skin wound repair is a multistage process involving multiple cellular and molecular
interactions, which modulate the cell behaviors and dynamic remodeling of extracellular …

Photothermal antibacterial materials to promote wound healing

L He, D Di, X Chu, X Liu, Z Wang, J Lu, S Wang… - Journal of Controlled …, 2023 - Elsevier
Wound healing is a crucial process that restores the integrity and function of the skin and
other tissues after injury. However, external factors, such as infection and inflammation, can …

Cutaneous wound healing: An update from physiopathology to current therapies

LFS Gushiken, FP Beserra, JK Bastos, CJ Jackson… - Life, 2021 - mdpi.com
The skin is the biggest organ of human body which acts as a protective barrier against
deleterious agents. When this barrier is damaged, the organism promotes the healing …

Advanced drug delivery systems and artificial skin grafts for skin wound healing

HS Kim, X Sun, JH Lee, HW Kim, X Fu… - Advanced drug delivery …, 2019 - Elsevier
Cutaneous injuries, especially chronic wounds, burns, and skin wound infection, require
painstakingly long-term treatment with an immense financial burden to healthcare systems …

Advancements in nanofibers for wound dressing: A review

RS Ambekar, B Kandasubramanian - European Polymer Journal, 2019 - Elsevier
Chronic wound healing is an intricate time-consuming process (healing time∼ 12 weeks),
susceptible to external biological attack such as bacteria (eg E. coli, B. subtilis, S. aureus …

MYC targeting by OMO-103 in solid tumors: a phase 1 trial

E Garralda, ME Beaulieu, V Moreno… - Nature Medicine, 2024 - nature.com
Among the 'most wanted'targets in cancer therapy is the oncogene MYC, which coordinates
key transcriptional programs in tumor development and maintenance. It has, however, long …

Re-epithelialization of adult skin wounds: Cellular mechanisms and therapeutic strategies

P Rousselle, F Braye, G Dayan - Advanced Drug Delivery Reviews, 2019 - Elsevier
Cutaneous wound healing in adult mammals is a complex multi-step process involving
overlapping stages of blood clot formation, inflammation, re-epithelialization, granulation …

Wound repair and regeneration: mechanisms, signaling, and translation

SA Eming, P Martin, M Tomic-Canic - Science translational medicine, 2014 - science.org
The cellular and molecular mechanisms underpinning tissue repair and its failure to heal are
still poorly understood, and current therapies are limited. Poor wound healing after trauma …

Epithelialization in wound healing: a comprehensive review

I Pastar, O Stojadinovic, NC Yin, H Ramirez… - Advances in wound …, 2014 - liebertpub.com
Significance: Keratinocytes, a major cellular component of the epidermis, are responsible for
restoring the epidermis after injury through a process termed epithelialization. This review …