Simple Summary Lung cancer is a widespread malignant tumour with a high mortality and
morbidity rate and is frequently diagnosed in the middle and late stages when few therapies …

Low-dose computed tomography (LDCT) screening for lung cancer substantially reduces
mortality from lung cancer, as revealed in randomized controlled trials and meta-analyses …

Smoking is the main risk factor for lung cancer (LC), which is the leading cause of cancer-
related death worldwide. Independent randomized controlled trials, governmental and inter …

Importance The National Lung Screening Trial (NLST) found that screening for lung cancer
with low-dose computed tomography (CT) reduced lung cancer–specific and all-cause …

Several trials have shown that low-dose computed tomography-based lung cancer
screening (LCS) allows a substantial reduction in lung cancer-related mortality, carrying the …

Lung cancer (LC) is the leading cause of cancer-related death worldwide, mostly because
the lack of a screening program so far. Although smoking cessation has a central role in LC …

Simple Summary Environmental and occupational exposures have been historically related
with an increased risk of several diseases and, among these, different cancers. Up to date …

Radiology is integral to cancer care. Compared to molecular assays, imaging has its
advantages. Imaging as a noninvasive tool can assess the entirety of tumor unbiased by …

Compared to other malignancies, few studies have investigated the role of family history of
cancer (FHC) in patients with lung cancer, yielding largely heterogeneous results. We …

Lung cancer screening with low-dose computed tomography (LDCT) is associated with a
significant mortality reduction 1 and is currently approved for highrisk individuals. However …