Biological roles of adenine methylation in RNA
K Boulias, EL Greer - Nature Reviews Genetics, 2023 - nature.com
Abstract N 6-Methyladenosine (m6A) is one of the most abundant modifications of the
epitranscriptome and is found in cellular RNAs across all kingdoms of life. Advances in …
epitranscriptome and is found in cellular RNAs across all kingdoms of life. Advances in …
The proteins of mRNA modification: writers, readers, and erasers
MN Flamand, M Tegowski… - Annual review of …, 2023 - annualreviews.org
Over the past decade, mRNA modifications have emerged as important regulators of gene
expression control in cells. Fueled in large part by the development of tools for detecting …
expression control in cells. Fueled in large part by the development of tools for detecting …
A unified model for the function of YTHDF proteins in regulating m6A-modified mRNA
S Zaccara, SR Jaffrey - Cell, 2020 - cell.com
Summary N 6-methyladenosine (m 6 A) is the most abundant mRNA nucleotide modification
and regulates critical aspects of cellular physiology and differentiation. m 6 A is thought to …
and regulates critical aspects of cellular physiology and differentiation. m 6 A is thought to …
Reading, writing and erasing mRNA methylation
S Zaccara, RJ Ries, SR Jaffrey - Nature reviews Molecular cell biology, 2019 - nature.com
RNA methylation to form N 6-methyladenosine (m6A) in mRNA accounts for the most
abundant mRNA internal modification and has emerged as a widespread regulatory …
abundant mRNA internal modification and has emerged as a widespread regulatory …
The m6A reader YTHDF1 promotes ovarian cancer progression via augmenting EIF3C translation
T Liu, Q Wei, J Jin, Q Luo, Y Liu, Y Yang… - Nucleic acids …, 2020 - academic.oup.com
Abstract N 6-Methyladenosine (m6A) is the most abundant RNA modification in mammal
mRNAs and increasing evidence suggests the key roles of m6A in human tumorigenesis …
mRNAs and increasing evidence suggests the key roles of m6A in human tumorigenesis …
The role of m6A RNA methylation in human cancer
XY Chen, J Zhang, JS Zhu - Molecular cancer, 2019 - Springer
Abstract N 6-methyladenosine (m 6 A) is identified as the most common, abundant and
conserved internal transcriptional modification, especially within eukaryotic messenger …
conserved internal transcriptional modification, especially within eukaryotic messenger …
m6A enhances the phase separation potential of mRNA
RJ Ries, S Zaccara, P Klein, A Olarerin-George… - Nature, 2019 - nature.com
Abstract N 6-methyladenosine (m6A) is the most prevalent modified nucleotide in mRNA,,
with around 25% of mRNAs containing at least one m6A. Methylation of mRNA to form m6A …
with around 25% of mRNAs containing at least one m6A. Methylation of mRNA to form m6A …
[HTML][HTML] RNA methylation and cancer treatment
To this date, over 100 different types of RNA modification have been identified. Methylation
of different RNA species has emerged as a critical regulator of transcript expression. RNA …
of different RNA species has emerged as a critical regulator of transcript expression. RNA …
The RNA modification N6-methyladenosine as a novel regulator of the immune system
Z Shulman, N Stern-Ginossar - Nature immunology, 2020 - nature.com
Protection from harmful pathogens depends on activation of the immune system, which
relies on tight regulation of gene expression. Recently, the RNA modification N 6 …
relies on tight regulation of gene expression. Recently, the RNA modification N 6 …
Dynamic RNA modifications in gene expression regulation
Over 100 types of chemical modifications have been identified in cellular RNAs. While the
5′ cap modification and the poly (A) tail of eukaryotic mRNA play key roles in regulation …
5′ cap modification and the poly (A) tail of eukaryotic mRNA play key roles in regulation …