We review progress towards greater mechanistic understanding and clinical translation of a
strategy to improve respiratory and non-respiratory motor function in people with …

Hypoxia is involved in the regulation of various cell functions in the body, including the
regulation of stem cells. The hypoxic microenvironment is indispensable from embryonic …

Substantial advances have been made recently into the discovery of fundamental
mechanisms underlying the neural control of breathing and even some inroads into …

Objective. To test the hypothesis that an anti-inflammatory corticosteroid drug enhances
spinal motor plasticity induced by acute intermittent hypoxia (AIH) in persons with chronic …

Motor skill acquisition depends on central nervous plasticity. However, behavioural
determinants leading to long lasting corticospinal plasticity and motor expertise remain …

Paired corticospinal-motoneuronal stimulation (PCMS) elicits spinal synaptic plasticity in
humans with chronic incomplete cervical spinal cord injury (SCI). Here, we examined …

Parkinson's disease (PD) is a progressive neurodegenerative disorder for which only
symptomatic treatments are available. Both preclinical and clinical studies suggest that …

Spinal cord injury (SCI) often results in impaired or absent sensorimotor function below the
level of the lesion. Recent electrophysiological studies in humans with chronic incomplete …

Remyelination and neurodegeneration prevention mitigate disability in Multiple Sclerosis
(MS). We have shown acute intermittent hypoxia (AIH) is a novel, non‐invasive and effective …

Acute intermittent hypoxia (AIH) elicits long‐term facilitation (LTF) of respiration. Although
LTF is observed when CO2 is elevated during AIH in awake humans, the influence of CO2 …