Exploring N6-methyladenosine (m6A) modification in tree species: opportunities and challenges

M Ramakrishnan, KS Rajan, S Mullasseri… - Horticulture …, 2024 - academic.oup.com
Abstract N 6-methyladenosine (m6A) in eukaryotes is the most common and widespread
internal modification in mRNA. The modification regulates mRNA stability, translation …

RMBase v3. 0: decode the landscape, mechanisms and functions of RNA modifications

J Xuan, L Chen, Z Chen, J Pang, J Huang… - Nucleic Acids …, 2024 - academic.oup.com
Although over 170 chemical modifications have been identified, their prevalence,
mechanism and function remain largely unknown. To enable integrated analysis of diverse …

A brief review of machine learning methods for RNA methylation sites prediction

H Wang, S Wang, Y Zhang, S Bi, X Zhu - Methods, 2022 - Elsevier
Thanks to the tremendous advancement of deep sequencing and large-scale profiling,
epitranscriptomics has become a rapidly growing field. As one of the most important parts of …

m6A-TSHub: Unveiling the Context-Specific m6A Methylation and m6A-Affecting Mutations in 23 Human Tissues

B Song, D Huang, Y Zhang, Z Wei, J Su… - Genomics …, 2023 - academic.oup.com
As the most pervasive epigenetic marker present on mRNAs and long non-coding RNAs
(lncRNAs), N 6-methyladenosine (m6A) RNA methylation has been shown to participate in …

A systematic review of non-coding RNA genes with differential expression profiles associated with autism spectrum disorders

J Stott, T Wright, J Holmes, J Wilson, S Griffiths-Jones… - Plos one, 2023 - journals.plos.org
Aims To identify differential expression of shorter non-coding RNA (ncRNA) genes
associated with autism spectrum disorders (ASD). Background ncRNA are functional …

Current status of epitranscriptomic marks affecting lncRNA structures and functions

HE Miller, M Ilieva, AJR Bishop, S Uchida - Non-coding RNA, 2022 - mdpi.com
Long non-coding RNAs (lncRNAs) belong to a class of non-protein-coding RNAs with their
lengths longer than 200 nucleotides. Most of the mammalian genome is transcribed as RNA …

[HTML][HTML] Recent advances in functional annotation and prediction of the epitranscriptome

SY Zhang, SW Zhang, T Zhang, XN Fan… - Computational and …, 2021 - Elsevier
RNA modifications, in particular N 6-methyladenosine (m 6 A), participate in every stages of
RNA metabolism and play diverse roles in essential biological processes and disease …

RNA epigenetics in chronic lung diseases

X Wang, Z Guo, F Yan - Genes, 2022 - mdpi.com
Chronic lung diseases are highly prevalent worldwide and cause significant mortality. Lung
cancer is the end stage of many chronic lung diseases. RNA epigenetics can dynamically …

A review on the role of RNA methylation in aging-related diseases

H Wei, Y Xu, L Lin, Y Li, X Zhu - International Journal of Biological …, 2024 - Elsevier
Senescence is the underlying mechanism of organism aging and is robustly regulated at the
post-transcriptional level. This regulation involves the chemical modifications, of which the …

RNA N6-Methyladenosine Modification in DNA Damage Response and Cancer Radiotherapy

C Wang, S Yao, T Zhang, X Sun, C Bai… - International Journal of …, 2024 - mdpi.com
The N6-methyladenosine (M6A) modification is the most common internal chemical
modification of RNA molecules in eukaryotes. This modification can affect mRNA …