Perspective: Coarse-grained models for biomolecular systems

WG Noid - The Journal of chemical physics, 2013 - pubs.aip.org
By focusing on essential features, while averaging over less important details, coarse-
grained (CG) models provide significant computational and conceptual advantages with …

Normal mode analysis of biomolecular structures: functional mechanisms of membrane proteins

I Bahar, TR Lezon, A Bakan, IH Shrivastava - Chemical reviews, 2010 - ACS Publications
A polymer chain of N atoms enjoys 3N-6 internal degrees of freedom, which gives rise to
infinitely many conformations. Even a simple model of N) 100 atoms where bond lengths …

Biomimetic hydrogel‐based actuating systems

L Ionov - Advanced Functional Materials, 2013 - Wiley Online Library
Active motion is intrinsic to all kinds of living organisms from unicellular ones to humans and
inspires development of synthetic actively moving materials. Hydrogels, which are three …

Combining an elastic network with a coarse-grained molecular force field: structure, dynamics, and intermolecular recognition

X Periole, M Cavalli, SJ Marrink… - Journal of chemical …, 2009 - ACS Publications
Structure-based and physics-based coarse-grained molecular force fields have become
attractive approaches to gain mechanistic insight into the function of large biomolecular …

Designing of a multi-epitope vaccine against the structural proteins of marburg virus exploiting the immunoinformatics approach

SA Sami, KKS Marma, S Mahmud, MAN Khan… - ACS …, 2021 - ACS Publications
Marburg virus disease (MVD) caused by the Marburg virus (MARV) generally appears with
flu-like symptoms and leads to severe hemorrhagic fever. It spreads via direct contact with …

Global dynamics of proteins: bridging between structure and function

I Bahar, TR Lezon, LW Yang… - Annual review of …, 2010 - annualreviews.org
Biomolecular systems possess unique, structure-encoded dynamic properties that underlie
their biological functions. Recent studies indicate that these dynamic properties are …

[图书][B] Coarse-graining of condensed phase and biomolecular systems

GA Voth - 2008 - taylorfrancis.com
Exploring recent developments in the field, Coarse-Graining of Condensed Phase and
Biomolecular Systems examines systematic ways of constructing coarse-grained …

A molecular modelling approach for identifying antiviral selenium-containing heterocyclic compounds that inhibit the main protease of SARS-CoV-2: an in silico …

A Rakib, Z Nain, SA Sami, S Mahmud… - Briefings in …, 2021 - academic.oup.com
Abstract Coronavirus disease 2019 (COVID-19), an infectious disease caused by the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been declared a global …

iMod: multipurpose normal mode analysis in internal coordinates

JR Lopéz-Blanco, JI Garzón, P Chacón - Bioinformatics, 2011 - academic.oup.com
Motivation: Dynamic simulations of systems with biologically relevant sizes and time scales
are critical for understanding macromolecular functioning. Coarse-grained representations …

Stochastic mechano-chemical kinetics of molecular motors: a multidisciplinary enterprise from a physicist's perspective

D Chowdhury - Physics Reports, 2013 - Elsevier
A molecular motor is made of either a single macromolecule or a macromolecular complex.
Just like their macroscopic counterparts, molecular motors “transduce” input energy into …