The rearranged during transfection (RET) proto-oncogene was identified in 1985 and, very
soon thereafter, a rearrangement named RET/PTC was discovered in papillary thyroid …

Objective: To describe the evolution and clinical utility of molecular testing for thyroid
nodules and cancer achieved over the last 2 decades. Methods: Scientific reports on thyroid …

Objective: To develop evidence-based recommendations for safe, effective, and appropriate
thyroidectomy. Background: Surgical management of thyroid disease has evolved …

Importance Approximately 20% of fine-needle aspirations (FNA) of thyroid nodules have
indeterminate cytology, most frequently Bethesda category III or IV. Diagnostic surgeries can …

Simple Summary Only about 4% of thyroid nodules are carcinomas and require surgery.
Fine-needle aspiration cytology is the most accurate tool to distinguish benign from …

Context Comprehensive genomic analysis of thyroid nodules for multiple classes of
molecular alterations detected in a large series of fine needle aspiration (FNA) samples has …

Thyroid carcinoma is the most frequent endocrine neoplasia. Different types of thyroid
carcinoma are described: well-differentiated papillary thyroid carcinoma (PTC), poorly …

PURPOSE In 2014, data from a comprehensive multiplatform analysis of 496 adult papillary
thyroid cancer samples reported by The Cancer Genome Atlas project suggested that …

Background: Some patients with metastatic differentiated thyroid cancer (DTC) lack iodine
avidity and are therefore unsuitable for radioactive iodine (RAI) therapy. Limited experience …

Thyroid carcinoma is the most common cancer in the endocrine system. Recent advances,
using next-generation sequencing, have shed light on the molecular pathogenesis of thyroid …