Frailty is a clinical syndrome characterized by a reduced physiologic reserve, increased
vulnerability to stressors and an increased risk of adverse outcomes. People with atrial …

Background Frailty is a common and clinically significant condition among geriatric
populations. Although well-evidenced pooled estimates of the prevalence of frailty exist …

Background despite a large and growing population of older people with frailty and atrial
fibrillation (AF), there is a lack of guidance on optimal AF management in this high-risk …

Background Frailty predicts poorer outcomes and decreased anticoagulation use in patients
with nonvalvular atrial fibrillation. We sought to assess the effectiveness and safety of …

Background Clinical frailty is an important syndrome for clinical care and research,
independently predicting mortality and rates of institutionalisation in a range of medical …

Background Patients with atrial fibrillation (AF) and frailty are a considerable group in clinical
practice. However, existing studies provide insufficient evidence of anticoagulation …

Atrial fibrillation (AF) is a common cardiac arrhythmia and its prevalence increases with age.
There is a significant correlation between frailty, morbidity and mortality in elderly patients …

OBJECTIVES Oral anticoagulants are the cornerstone of stroke prevention in high‐risk
patients with atrial fibrillation (AF). Geriatric elements, such as cognitive impairment and …

Background: Frail patients with atrial fibrillation (AF) are less likely to receive anticoagulation
than nonfrail patients with AF despite frailty being associated with poorer clinical outcomes …

Background Patient frailty amongst patients with nonvalvular atrial fibrillation (NVAF) is
associated with adverse health outcomes and increased risk of mortality. Additional …