Activated choline metabolism is a hallmark of carcinogenesis and tumor progression, which
leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …

Phospholipids are suggested to drive tumorigenesis through their essential role in
inflammation. Phospholipase A2 (PLA2) is a phospholipid metabolizing enzyme that …

An activatable nanoprobe for imaging breast cancer metastases through near infrared‐I
(NIR‐I)/NIR‐II fluorescence imaging and multispectral optoacoustic tomography (MSOT) …

Background Cholangiocarcinoma (CCA), consisting of intrahepatic (IHCCA), perihilar
(PHCCA), and distal (DCCA) CCA, is a type of highly aggressive malignancy with a very …

Purpose This work aims to identify differential metabolites and predicting molecular
subtypes of breast cancer (BC). Methods Plasma samples were collected from 96 BC …

Dysregulation of fatty acid metabolism and de novo lipogenesis is a key driver of several
cancer types through highly unsaturated fatty acid (HUFA) signaling precursors such as …

Target-specific treatment modalities are currently not available for triple-negative breast
cancer (TNBC), and acquired chemotherapy resistance is a primary obstacle for the …

Simple Summary Breast cancer is the leading cause of female cancer-related deaths
worldwide. New technologies with enhanced sensitivity and specificity for early diagnosis …

Introduction: Phospholipases A2 have been implicated in various pathological conditions,
such as rheumatoid arthritis, cardiovascular diseases, neurological disorders and cancer …

Abstract Epidermal Growth Factor Receptor (EGFR) signaling and EGFR mutations play key
roles in cancer pathogenesis, particularly in the development of drug resistance. For the∼ …