Consensus guidelines for the use and interpretation of angiogenesis assays
The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …
important roles in growth and development, tissue and organ regeneration, as well as …
Integral utilization of red seaweed for bioactive production
The hydrocolloids carrageenan and agar are the major fraction industrially extracted and
commercialized from red seaweeds. However, this type of macroalgae also contains a …
commercialized from red seaweeds. However, this type of macroalgae also contains a …
Dynamic endothelial cell rearrangements drive developmental vessel regression
Patterning of functional blood vessel networks is achieved by pruning of superfluous
connections. The cellular and molecular principles of vessel regression are poorly …
connections. The cellular and molecular principles of vessel regression are poorly …
The control of vascular integrity by endothelial cell junctions: molecular basis and pathological implications
E Dejana, E Tournier-Lasserve, BM Weinstein - Developmental cell, 2009 - cell.com
Human pathologies such as vascular malformations, hemorrhagic stroke, and edema have
been associated with defects in the organization of endothelial cell junctions. Understanding …
been associated with defects in the organization of endothelial cell junctions. Understanding …
Extracellular control of TGFβ signalling in vascular development and disease
P Ten Dijke, HM Arthur - Nature reviews Molecular cell biology, 2007 - nature.com
The intracellular mechanism of transforming growth factor-β (TGFβ) signalling via kinase
receptors and SMAD effectors is firmly established, but recent studies of human …
receptors and SMAD effectors is firmly established, but recent studies of human …
BMP9 mutations cause a vascular-anomaly syndrome with phenotypic overlap with hereditary hemorrhagic telangiectasia
WL Wooderchak-Donahue, J McDonald… - The American Journal of …, 2013 - cell.com
Hereditary hemorrhagic telangiectasia (HHT), the most common inherited vascular disorder,
is caused by mutations in genes involved in the transforming growth factor beta (TGF-β) …
is caused by mutations in genes involved in the transforming growth factor beta (TGF-β) …
Signaling by members of the TGF-β family in vascular morphogenesis and disease
E Pardali, MJ Goumans, P ten Dijke - Trends in cell biology, 2010 - cell.com
Members of the transforming growth factor-β (TGF-β) family play pivotal roles in
development and disease. These cytokines elicit their pleiotropic effects on cells, including …
development and disease. These cytokines elicit their pleiotropic effects on cells, including …
Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells
ALK1 is an endothelial-specific type I receptor of the TGFβ receptor family whose
heterozygous mutations cause hereditary hemorrhagic telangiectasia type 2. Although …
heterozygous mutations cause hereditary hemorrhagic telangiectasia type 2. Although …
[HTML][HTML] ALK1 signaling inhibits angiogenesis by cooperating with the Notch pathway
Activin receptor-like kinase 1 (ALK1) is an endothelial-specific member of the TGF-β/BMP
receptor family that is inactivated in patients with hereditary hemorrhagic telangiectasia …
receptor family that is inactivated in patients with hereditary hemorrhagic telangiectasia …
Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries
AF Siekmann, ND Lawson - Nature, 2007 - nature.com
Recent evidence indicates that growing blood-vessel sprouts consist of endothelial cells
with distinct cell fates and behaviours,; however, it is not clear what signals determine these …
with distinct cell fates and behaviours,; however, it is not clear what signals determine these …