The rapid expansion of next‐generation sequencing has yielded a powerful array of tools to
address fundamental biological questions at a scale that was inconceivable just a few years …

Levels and patterns of genetic diversity can provide insights into a population's history. In
species with sex chromosomes, differences between genomic regions with unique …

Unlike copy number variants (CNVs), inversions remain an underexplored genetic variation
class. By integrating multiple genomic technologies, we discover 729 inversions in 41 …

It has been shown that Neanderthals contributed genetically to modern humans outside
Africa 47,000–65,000 years ago. Here we analyse the genomes of a Neanderthal and a …

Abstract Approximately 2–4% of genetic material in human populations outside Africa is
derived from Neanderthals who interbred with anatomically modern humans. Recent studies …

Deleterious mutations continuously accumulate in populations, building up a burden that
can threaten their survival, particularly in small populations when inbreeding exposes …

While it is appreciated that population size changes can impact patterns of deleterious
variation in natural populations, less attention has been paid to how gene flow affects and is …

A faster rate of adaptive evolution of X‐linked genes compared with autosomal genes can
be caused by the fixation of recessive or partially recessive advantageous mutations, due to …

Rhesus macaques (Macaca mulatta) are the most widely used nonhuman primate in
biomedical research, have the largest natural geographic distribution of any nonhuman …

Levels and patterns of genetic diversity can provide insights into a population's history. In
species with sex chromosomes, differences between genomic regions with unique …