New perspectives on sex differences in learning and memory

AW Fleischer, KM Frick - Trends in Endocrinology & Metabolism, 2023 - cell.com
Females have historically been disregarded in memory research, including the thousands of
studies examining roles for the hippocampus, medial prefrontal cortex, and amygdala in …

[HTML][HTML] Sex-dependent differences in animal cognition

A Koszałka, K Lustyk, K Pytka - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
The differences in cognitive processes driven by biological sex are the issues that have
gotten growing attention recently. Considering the increasing population suffering from …

A fear conditioned cue orchestrates a suite of behaviors in rats

A Chu, NT Gordon, AM DuBois, CB Michel… - Elife, 2024 - elifesciences.org
Pavlovian fear conditioning has been extensively used to study the behavioral and neural
basis of defensive systems. In a typical procedure, a cue is paired with foot shock, and …

Conditional and unconditional components of aversively motivated freezing, flight and darting in mice

JM Trott, AN Hoffman, I Zhuravka, MS Fanselow - Elife, 2022 - elifesciences.org
Fear conditioning is one of the most frequently used laboratory procedures for modeling
learning and memory generally, and anxiety disorders in particular. The conditional …

Behavioral neuroscience's inevitable SABV growing pains

RM Shansky - Trends in Neurosciences, 2024 - cell.com
The field of rodent behavioral neuroscience is undergoing two major sea changes: an ever-
growing technological revolution, and worldwide calls to consider sex as a biological …

Increased reactivity of the paraventricular nucleus of the hypothalamus and decreased threat responding in male rats following psilocin administration

DP Effinger, JL Hoffman, SE Mott, SN Magee… - Nature …, 2024 - nature.com
Psychedelics have experienced renewed interest following positive clinical effects, however
the neurobiological mechanisms underlying effects remain unclear. The paraventricular …

Multiple factors contribute to flight behaviors during fear conditioning

T Furuyama, A Imayoshi, T Iyobe, M Ono, T Ishikawa… - Scientific Reports, 2023 - nature.com
Shifting defensive mode from one to another by the imminence of threat is crucial for
survival. The transition of defensive mode from freezing to flight is observed during the …

[HTML][HTML] Pharmacological modulation of Kv3 voltage-gated potassium channels regulates fear discrimination and expression in a response-dependent manner

C Stubbendorff, E Hale, HLL Day, J Smith… - Progress in Neuro …, 2023 - Elsevier
Various psychiatric diseases are characterized by aberrant cognition and emotional
regulation. This includes inappropriately attributing affective salience to innocuous cues …

CB1R blockade unmasks TRPV1-mediated contextual fear generalization in female, but not male rats

KA Huckleberry, R Calitri, AJ Li, M Mejdell… - …, 2023 - nature.com
Increasing evidence suggests that the neurobiological processes that govern learning and
memory can be different in males and females, but many of the specific mechanisms …

On making (and turning adaptive to) maladaptive aversive memories in laboratory rodents

L Gazarini, CAJ Stern, LJ Bertoglio - Neuroscience & Biobehavioral …, 2023 - Elsevier
Fear conditioning and avoidance tasks usually elicit adaptive aversive memories. Traumatic
memories are more intense, generalized, inflexible, and resistant to attenuation via …