Clinical trials of stem cell therapy for cerebral ischemic stroke
M Kawabori, H Shichinohe, S Kuroda… - International Journal of …, 2020 - mdpi.com
Despite recent developments in innovative treatment strategies, stroke remains one of the
leading causes of death and disability worldwide. Stem cell therapy is currently attracting …
leading causes of death and disability worldwide. Stem cell therapy is currently attracting …
Introduction to stem cells and regenerative medicine
Stem cells are a population of undifferentiated cells characterized by the ability to
extensively proliferate (self-renewal), usually arise from a single cell (clonal), and …
extensively proliferate (self-renewal), usually arise from a single cell (clonal), and …
Clinical outcomes of transplanted modified bone marrow–derived mesenchymal stem cells in stroke: a phase 1/2a study
GK Steinberg, D Kondziolka, LR Wechsler… - Stroke, 2016 - Am Heart Assoc
Background and Purpose—Preclinical data suggest that cell-based therapies have the
potential to improve stroke outcomes. Methods—Eighteen patients with stable, chronic …
potential to improve stroke outcomes. Methods—Eighteen patients with stable, chronic …
Two-year safety and clinical outcomes in chronic ischemic stroke patients after implantation of modified bone marrow–derived mesenchymal stem cells (SB623): a …
GK Steinberg, D Kondziolka, LR Wechsler… - Journal of …, 2018 - thejns.org
OBJECTIVE The aim of this study was to evaluate the safety and clinical outcomes
associated with stereotactic surgical implantation of modified bone marrow–derived …
associated with stereotactic surgical implantation of modified bone marrow–derived …
Cell based therapies for ischemic stroke: from basic science to bedside
X Liu, R Ye, T Yan, SP Yu, L Wei, G Xu, X Fan… - Progress in …, 2014 - Elsevier
Cell therapy is emerging as a viable therapy to restore neurological function after stroke.
Many types of stem/progenitor cells from different sources have been explored for their …
Many types of stem/progenitor cells from different sources have been explored for their …
Defining and designing polymers and hydrogels for neural tissue engineering
The use of biomaterials, such as hydrogels, as neural cell delivery devices is becoming
more common in areas of research such as stroke, traumatic brain injury, and spinal cord …
more common in areas of research such as stroke, traumatic brain injury, and spinal cord …
Stem cells in clinical practice: applications and warnings
D Lodi, T Iannitti, B Palmieri - Journal of Experimental & Clinical Cancer …, 2011 - Springer
Stem cells are a relevant source of information about cellular differentiation, molecular
processes and tissue homeostasis, but also one of the most putative biological tools to treat …
processes and tissue homeostasis, but also one of the most putative biological tools to treat …
Stem cell therapy: a clinical trial of stroke
A Bhasin, MVP Srivastava, S Mohanty, R Bhatia… - Clinical neurology and …, 2013 - Elsevier
BACKGROUND: The alarming disability burden and a high prevalence rate of stroke in India
has encouraged the researchers to develop regenerative therapies to reduce clinical …
has encouraged the researchers to develop regenerative therapies to reduce clinical …
[图书][B] Intervening in the brain: changing psyche and society
R Merkel, G Boer, J Fegert, T Galert, D Hartmann… - 2007 - Springer
The Europäische Akademie is concerned with the study of the consequences of scientific
and technological advance both for the individual and for society at large as well as for the …
and technological advance both for the individual and for society at large as well as for the …
Stem cell therapy and administration routes after stroke
B Rodríguez-Frutos, L Otero-Ortega… - Translational stroke …, 2016 - Springer
Cell-based therapy has demonstrated safety and efficacy in experimental animal models of
stroke, as well as safety in stroke patients. However, various questions remain regarding the …
stroke, as well as safety in stroke patients. However, various questions remain regarding the …