Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets

B Chen, P Yu, WN Chan, F Xie, Y Zhang… - … and Targeted Therapy, 2024 - nature.com
Zinc metabolism at the cellular level is critical for many biological processes in the body. A
key observation is the disruption of cellular homeostasis, often coinciding with disease …

[HTML][HTML] Zinc at the crossroads of exercise and proteostasis

JD Hernández-Camacho, C Vicente-García… - Redox biology, 2020 - Elsevier
Zinc is an essential element for all forms of life, and one in every ten human proteins is a
zinc protein. Zinc has catalytic, structural and signalling functions and its correct …

[HTML][HTML] Integrated design and fabrication strategies based on bioprinting for skeletal muscle regeneration: current status and future perspectives

H Ma, F Xing, P Yu, J Xu, X Wu, R Luo, Z Xiang… - Materials & Design, 2023 - Elsevier
The number of skeletal muscle injuries derived from myopathies, exercise, and trauma, is
growing due to increasing sports activities in normal life of people. Skeletal muscle has a …

Bio-nanocomposite hydrogel based on zinc alginate/graphene oxide: morphology, structural conformation, thermal behavior/degradation, and dielectric properties

R Sabater i Serra, J Molina-Mateo… - Polymers, 2020 - mdpi.com
Bio-nanocomposite hydrogels based on sodium alginate (SA) as polymer matrix and
graphene oxide (GO) nanosheets with zinc as crosslinking agent were synthesized with the …

[HTML][HTML] Ionic medicine: exploiting metallic ions to stimulate skeletal muscle tissue regeneration

HH Lu, D Ege, S Salehi, AR Boccaccini - Acta Biomaterialia, 2024 - Elsevier
The regeneration of healthy and functional skeletal muscle at sites of injuries and defects
remains a challenge. Mimicking the natural environment surrounding skeletal muscle cells …

Zinc‐induced SUMOylation of dynamin‐related protein 1 protects the heart against ischemia‐reperfusion injury

X Bian, J Xu, H Zhao, Q Zheng, X Xiao… - Oxidative medicine …, 2019 - Wiley Online Library
Background. Zinc plays a role in mitophagy and protects cardiomyocytes from
ischemia/reperfusion injury. This study is aimed at investigating whether SUMOylation of …

Zinc oxide nanoparticles promoting the formation of myogenic differentiation into myotubes in mouse myoblast C2C12 cells

V Ramalingam, I Hwang - Journal of Industrial and Engineering Chemistry, 2020 - Elsevier
In the present study, we investigated the effect of monodispersed zinc oxide (ZnO)
nanoparticles on the proliferation, myogenic differentiation and regulation of associated …

Zinc modulates several transcription-factor regulated pathways in mouse skeletal muscle cells

P Vahidi Ferdowsi, R Ng, J Adulcikas, SS Sohal… - Molecules, 2020 - mdpi.com
Zinc is an essential metal ion involved in many biological processes. Studies have shown
that zinc can activate several molecules in the insulin signalling pathway and the …

Maternal methyl-donor micronutrient supplementation during pregnancy promotes skeletal muscle differentiation and maturity in newborn and weaning pigs

Q He, T Zou, J Chen, L Jian, J He, Y Xia, F Xie… - Frontiers in …, 2020 - frontiersin.org
Adequate maternal methyl-donor micronutrient (MET) intake is an important determinant of
the organ development and metabolic renovation of offspring. The mechanism involved in …

ZIP transporters‐regulated Zn2+ homeostasis: A novel determinant of human diseases

H Liu, L Li, R Lu - Journal of Cellular Physiology, 2024 - Wiley Online Library
As an essential trace element for organisms, zinc participates in various physiological
processes, such as RNA transcription, DNA replication, cell proliferation, and cell …