A dynamic and mutualistic interaction between tumour cells and the surrounding stroma
promotes the initiation, progression, metastasis and chemoresistance of solid tumours. Far …

Neutrophils promptly accumulate in large numbers at sites of tissue injury. Injuries to the skin
or mucosae disrupt barriers against the external environment, and the bactericidal actions of …

INTRODUCTION Resident tissue macrophages (RTMs) are a heterogeneous population of
immune cells occupying multiple tissue niches and exhibiting microenvironment-specific …

Despite the significant technological advancement in tissue engineering, challenges still
exist towards the development of complex and fully functional tissue constructs that mimic …

The maintenance of appropriate arterial tone is critically important for normal physiological
arterial function. However, the cellular and molecular mechanisms remain poorly defined …

Despite advances in the bioprinting technology, biofabrication of circumferentially
multilayered tubular tissues or organs with cellular heterogeneity, such as blood vessels …

Neural (N)-cadherin is a calcium-dependent single-chain transmembrane glycoprotein that
mediates homotypic and heterotypic cell-cell adhesion. As an important member of the …

Angiogenesis is a vital process for the growth and dissemination of solid cancers. Numerous
molecular pathways are known to drive angiogenic switch in cancer cells promoting the …

The intestinal extracellular matrix (ECM) represents a complex network of proteins that not
only forms a support structure for resident cells but also interacts closely with them by …

Diabetic retinopathy remains a relevant clinical problem. In parallel with diagnostic and
therapeutic improvements, the role of glycaemia and reactive metabolites causing cell stress …