[HTML][HTML] Rationale for the use of N‐acetylcysteine in both prevention and adjuvant therapy of COVID‐19
S De Flora, R Balansky, S La Maestra - The FASEB journal, 2020 - ncbi.nlm.nih.gov
COVID‐19 may cause pneumonia, acute respiratory distress syndrome, cardiovascular
alterations, and multiple organ failure, which have been ascribed to a cytokine storm, a …
alterations, and multiple organ failure, which have been ascribed to a cytokine storm, a …
Redox biology of respiratory viral infections
Respiratory viruses cause infections of the upper or lower respiratory tract and they are
responsible for the common cold—the most prevalent disease in the world. In many cases …
responsible for the common cold—the most prevalent disease in the world. In many cases …
Glutathione: new roles in redox signaling for an old antioxidant
K Aquilano, S Baldelli, MR Ciriolo - Frontiers in pharmacology, 2014 - frontiersin.org
The physiological roles played by the tripeptide glutathione have greatly advanced over the
past decades superimposing the research on free radicals, oxidative stress and, more …
past decades superimposing the research on free radicals, oxidative stress and, more …
Pathogen recognition by the innate immune system
Microbial infection initiates complex interactions between the pathogen and the host.
Pathogens express several signature molecules, known as pathogen-associated molecular …
Pathogens express several signature molecules, known as pathogen-associated molecular …
Glutathione dysregulation and the etiology and progression of human diseases
Glutathione (GSH) plays an important role in a multitude of cellular processes, including cell
differentiation, proliferation, and apoptosis, and as a result, disturbances in GSH …
differentiation, proliferation, and apoptosis, and as a result, disturbances in GSH …
Redox-modulating agents in the treatment of viral infections
P Checconi, M De Angelis, ME Marcocci… - International Journal of …, 2020 - mdpi.com
Viruses use cell machinery to replicate their genome and produce viral proteins. For this
reason, several intracellular factors, including the redox state, might directly or indirectly …
reason, several intracellular factors, including the redox state, might directly or indirectly …
Ferroptosis in viral infection: the unexplored possibility
M Wang, B Joshua, N Jin, S Du, C Li - Acta Pharmacologica Sinica, 2022 - nature.com
Virus-induced cell death has long been thought of as a double-edged sword in the inhibition
or exacerbation of viral infections. The vital role of iron, an essential element for various …
or exacerbation of viral infections. The vital role of iron, an essential element for various …
[HTML][HTML] Polyphenols and glutathione synthesis regulation
JØ Moskaug, H Carlsen, MCW Myhrstad… - The American journal of …, 2005 - Elsevier
Polyphenols in food plants are a versatile group of phytochemicals with many potentially
beneficial activities in terms of disease prevention. In vitro cell culture experiments have …
beneficial activities in terms of disease prevention. In vitro cell culture experiments have …
Role of glutathione in immunity and inflammation in the lung
P Ghezzi - International journal of general medicine, 2011 - Taylor & Francis
Reactive oxygen species and thiol antioxidants, including glutathione (GSH), regulate innate
immunity at various levels. This review outlines the redox-sensitive steps of the cellular …
immunity at various levels. This review outlines the redox-sensitive steps of the cellular …
Infectious agents and neurodegeneration
G De Chiara, ME Marcocci, R Sgarbanti, L Civitelli… - Molecular …, 2012 - Springer
A growing body of epidemiologic and experimental data point to chronic bacterial and viral
infections as possible risk factors for neurodegenerative diseases, including Alzheimer's …
infections as possible risk factors for neurodegenerative diseases, including Alzheimer's …