[HTML][HTML] Rationale for the use of N‐acetylcysteine in both prevention and adjuvant therapy of COVID‐19

S De Flora, R Balansky, S La Maestra - The FASEB journal, 2020 - ncbi.nlm.nih.gov
COVID‐19 may cause pneumonia, acute respiratory distress syndrome, cardiovascular
alterations, and multiple organ failure, which have been ascribed to a cytokine storm, a …

Redox biology of respiratory viral infections

OA Khomich, SN Kochetkov, B Bartosch, AV Ivanov - Viruses, 2018 - mdpi.com
Respiratory viruses cause infections of the upper or lower respiratory tract and they are
responsible for the common cold—the most prevalent disease in the world. In many cases …

Glutathione: new roles in redox signaling for an old antioxidant

K Aquilano, S Baldelli, MR Ciriolo - Frontiers in pharmacology, 2014 - frontiersin.org
The physiological roles played by the tripeptide glutathione have greatly advanced over the
past decades superimposing the research on free radicals, oxidative stress and, more …

Pathogen recognition by the innate immune system

H Kumar, T Kawai, S Akira - International reviews of immunology, 2011 - Taylor & Francis
Microbial infection initiates complex interactions between the pathogen and the host.
Pathogens express several signature molecules, known as pathogen-associated molecular …

Glutathione dysregulation and the etiology and progression of human diseases

N Ballatori, SM Krance, S Notenboom, S Shi, K Tieu… - 2009 - degruyter.com
Glutathione (GSH) plays an important role in a multitude of cellular processes, including cell
differentiation, proliferation, and apoptosis, and as a result, disturbances in GSH …

Redox-modulating agents in the treatment of viral infections

P Checconi, M De Angelis, ME Marcocci… - International Journal of …, 2020 - mdpi.com
Viruses use cell machinery to replicate their genome and produce viral proteins. For this
reason, several intracellular factors, including the redox state, might directly or indirectly …

Ferroptosis in viral infection: the unexplored possibility

M Wang, B Joshua, N Jin, S Du, C Li - Acta Pharmacologica Sinica, 2022 - nature.com
Virus-induced cell death has long been thought of as a double-edged sword in the inhibition
or exacerbation of viral infections. The vital role of iron, an essential element for various …

[HTML][HTML] Polyphenols and glutathione synthesis regulation

JØ Moskaug, H Carlsen, MCW Myhrstad… - The American journal of …, 2005 - Elsevier
Polyphenols in food plants are a versatile group of phytochemicals with many potentially
beneficial activities in terms of disease prevention. In vitro cell culture experiments have …

Role of glutathione in immunity and inflammation in the lung

P Ghezzi - International journal of general medicine, 2011 - Taylor & Francis
Reactive oxygen species and thiol antioxidants, including glutathione (GSH), regulate innate
immunity at various levels. This review outlines the redox-sensitive steps of the cellular …

Infectious agents and neurodegeneration

G De Chiara, ME Marcocci, R Sgarbanti, L Civitelli… - Molecular …, 2012 - Springer
A growing body of epidemiologic and experimental data point to chronic bacterial and viral
infections as possible risk factors for neurodegenerative diseases, including Alzheimer's …