[HTML][HTML] Benchmark of cellular deconvolution methods using a multi-assay reference dataset from postmortem human prefrontal cortex

LA Huuki-Myers, KD Montgomery, SH Kwon… - BioRxiv, 2024 - ncbi.nlm.nih.gov
Background: Cellular deconvolution of bulk RNA-sequencing (RNA-seq) data using single
cell or nuclei RNA-seq (sc/snRNA-seq) reference data is an important strategy for estimating …

[HTML][HTML] Distinctive Whole-brain Cell-Types Strongly Predict Tissue Damage Patterns in Eleven Neurodegenerative Disorders

V Pak, Q Adewale, D Bzdok, M Dadar, Y Zeighami… - eLife, 2023 - elifesciences.org
For over a century, brain research narrative has mainly centered on neuron cells.
Accordingly, most whole-brain neurodegenerative studies focus on neuronal dysfunction …

Distinctive whole-brain cell types predict tissue damage patterns in thirteen neurodegenerative conditions

V Pak, Q Adewale, D Bzdok, M Dadar, Y Zeighami… - Elife, 2024 - elifesciences.org
For over a century, brain research narrative has mainly centered on neuron cells.
Accordingly, most neurodegenerative studies focus on neuronal dysfunction and their …