[HTML][HTML] SARS-CoV-2 viral load and shedding kinetics

O Puhach, B Meyer, I Eckerle - Nature Reviews Microbiology, 2023 - nature.com
SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …

Therapeutics for COVID-19

SS Toussi, JL Hammond, BS Gerstenberger… - Nature …, 2023 - nature.com
Vaccines and monoclonal antibody treatments to prevent severe coronavirus disease 2019
(COVID-19) illness were available within a year of the pandemic being declared but there …

Phase III Pivotal comparative clinical trial of intranasal (iNCOVACC) and intramuscular COVID 19 vaccine (Covaxin®)

C Singh, S Verma, P Reddy, MS Diamond, DT Curiel… - npj Vaccines, 2023 - nature.com
One of the most preferable characteristics for a COVID-19 vaccine candidate is the ability to
reduce transmission and infection of SARS-CoV-2, in addition to disease prevention. Unlike …

Diagnostic accuracy of two commercial SARS-CoV-2 antigen-detecting rapid tests at the point of care in community-based testing centers

A Berger, MTN Nsoga, FJ Perez-Rodriguez, YA Aad… - Plos one, 2021 - journals.plos.org
Objectives Determine the diagnostic accuracy of two antigen-detecting rapid diagnostic tests
(Ag-RDT) for SARS-CoV-2 at the point of care and define individuals' characteristics …

Heterogeneity in transmissibility and shedding SARS-CoV-2 via droplets and aerosols

PZ Chen, N Bobrovitz, Z Premji, M Koopmans… - Elife, 2021 - elifesciences.org
Background: Which virological factors mediate overdispersion in the transmissibility of
emerging viruses remains a long-standing question in infectious disease epidemiology …

Infectious viral load in unvaccinated and vaccinated patients infected with SARS-CoV-2 WT, Delta and Omicron

O Puhach, K Adea, N Hulo, P Sattonnet, C Genecand… - MedRxiv, 2022 - medrxiv.org
Background Viral load (VL) is one determinant of secondary transmission of SARS-CoV-2.
Emergence of variants of concerns (VOC) Alpha and Delta was ascribed, at least partly, to …

Modelling upper respiratory viral load dynamics of SARS-CoV-2

JD Challenger, CY Foo, Y Wu, AWC Yan… - BMC medicine, 2022 - Springer
Relationships between viral load, severity of illness, and transmissibility of virus are
fundamental to understanding pathogenesis and devising better therapeutic and prevention …

SARS-CoV-2 shedding dynamics across the respiratory tract, sex, and disease severity for adult and pediatric COVID-19

PZ Chen, N Bobrovitz, ZA Premji, M Koopmans… - Elife, 2021 - elifesciences.org
Background: Previously, we conducted a systematic review and analyzed the respiratory
kinetics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)(Chen et al …

Mitigation of SARS-CoV-2 transmission at a large public university

DRE Ranoa, RL Holland, FG Alnaji, KJ Green… - Nature …, 2022 - nature.com
In Fall 2020, universities saw extensive transmission of SARS-CoV-2 among their
populations, threatening health of the university and surrounding communities, and viability …

Functionalized terpolymer-brush-based biointerface with improved antifouling properties for ultra-sensitive direct detection of virus in crude clinical samples

M Forinová, A Pilipenco, I Visova… - … applied materials & …, 2021 - ACS Publications
New analytical techniques that overcome major drawbacks of current routinely used viral
infection diagnosis methods, ie, the long analysis time and laboriousness of real-time …