Severe covid-19 pneumonia has posed critical challenges for the research and medical
communities. Older age, male sex, and comorbidities increase the risk for severe disease …

Abstract The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …

Rationale: One important concern during high-flow nasal cannula (HFNC) therapy in
patients with acute hypoxemic respiratory failure is to not delay intubation. Objectives: To …

Nasal high flow (NHF) has gained popularity among intensivists to manage patients with
acute respiratory failure. An important literature has accompanied this evolution. In this …

Noninvasive mechanical ventilation (NIV) is widely used in the acute care setting for acute
respiratory failure (ARF) across a variety of aetiologies. This document provides European …

Background High-flow nasal cannula (HFNC) is an emerging therapy for respiratory failure
but the extent of exhaled air dispersion during treatment is unknown. We examined exhaled …

Importance High-flow nasal oxygen therapy is increasingly used for acute hypoxemic
respiratory failure (AHRF). Objective To determine whether high-flow oxygen therapy …

Background In immunocompromised patients with acute hypoxemic respiratory failure
(ARF), initial management aims primarily to avoid invasive mechanical ventilation (IMV) …

Sepsis and septic shock are major causes of mortality during chemotherapy-induced
neutropenia for malignancies requiring urgent treatment. Thus, awareness of the presenting …

Background Although non-invasive ventilation (NIV) is recommended for
immunocompromised patients with acute respiratory failure in the intensive care unit (ICU), it …