Tyrosine-type site-specific recombinases (T-SSRs) have opened new avenues for the
predictable modification of genomes as they enable precise genome editing in heterologous …

Unlike copy number variants (CNVs), inversions remain an underexplored genetic variation
class. By integrating multiple genomic technologies, we discover 729 inversions in 41 …

Polymorphic inversions are a type of structural variants that are difficult to analyze owing to
their balanced nature and the location of breakpoints within complex repeated regions. So …

Understanding the role of chromosomal inversions in speciation is a fundamental problem in
evolutionary genetics. Here, we perform a comprehensive reconstruction of the evolutionary …

Although chromosome rearrangements (CRs) are central to studies of genome evolution,
our understanding of the evolutionary consequences of the early stages of karyotypic …

Inversions are one type of structural variants linked to phenotypic differences and adaptation
in multiple organisms. However, there is still very little information about polymorphic …

Polymorphic inversions are ubiquitous in humans and they have been linked to both
adaptation and disease. Following their discovery in Drosophila more than a century ago …

Abstract In this work, Corbett-Detig et al. use proximity-ligation sequencing (Hi-C) of several
Anopheles gambiae and A. coluzzii inversionbearing individuals to detect and map …

Human chromosome inversions are types of balanced structural variations, making them
difficult to analyze. Thanks to PEM (paired‐end sequencing and mapping), there has been …

Polymorphic inversions contribute to adaptation and phenotypic variation. However, large
multi-centric association studies of inversions remain challenging. We present scoreInvHap …