The role of lactoferrin in gastrointestinal and immune development and function: a preclinical perspective
SM Donovan - The Journal of pediatrics, 2016 - Elsevier
The early postnatal period is a critical time for gastrointestinal (GI) and immune
development. Neonates fed mother's milk have more rapid GI and immune development …
development. Neonates fed mother's milk have more rapid GI and immune development …
[HTML][HTML] Early-life nutrition and neurodevelopment: use of the piglet as a translational model
Optimal nutrition early in life is critical to ensure proper structural and functional
development of infant organ systems. Although pediatric nutrition historically has …
development of infant organ systems. Although pediatric nutrition historically has …
Serum cortisol mediates the relationship between fecal Ruminococcus and brain N-acetylaspartate in the young pig
AT Mudd, K Berding, M Wang, SM Donovan… - Gut …, 2017 - Taylor & Francis
ABSTRACT A dynamic relationship between the gut microbiota and brain is pivotal in
neonatal development. Dysbiosis of the microbiome may result in altered …
neonatal development. Dysbiosis of the microbiome may result in altered …
Dietary prebiotics, milk fat globule membrane, and lactoferrin affects structural neurodevelopment in the young piglet
AT Mudd, LS Alexander, K Berding… - Frontiers in …, 2016 - frontiersin.org
Introduction Milk fat globule membrane (MFGM) and lactoferrin have been identified as two
components that have potential to affect neurodevelopment. While concentrations of some …
components that have potential to affect neurodevelopment. While concentrations of some …
[HTML][HTML] Early supplementation of phospholipids and gangliosides affects brain and cognitive development in neonatal piglets
H Liu, EC Radlowski, MS Conrad, Y Li, RN Dilger… - The Journal of …, 2014 - Elsevier
Background: Because human breast milk is a rich source of phospholipids and gangliosides
and breastfed infants have improved learning compared with formula-fed infants, the …
and breastfed infants have improved learning compared with formula-fed infants, the …
[HTML][HTML] A porcine model of phenylketonuria generated by CRISPR/Cas9 genome editing
Phenylalanine hydroxylase–deficient (PAH-deficient) phenylketonuria (PKU) results in
systemic hyperphenylalaninemia, leading to neurotoxicity with severe developmental …
systemic hyperphenylalaninemia, leading to neurotoxicity with severe developmental …
Dietary sialyllactose influences sialic acid concentrations in the prefrontal cortex and magnetic resonance imaging measures in corpus callosum of young pigs
AT Mudd, SA Fleming, B Labhart, M Chichlowski… - Nutrients, 2017 - mdpi.com
Sialic acid (SA) is a key component of gangliosides and neural cell adhesion molecules
important during neurodevelopment. Human milk contains SA in the form of sialyllactose …
important during neurodevelopment. Human milk contains SA in the form of sialyllactose …
Delayed growth, motor function and learning in preterm pigs during early postnatal life
AD Andersen, PT Sangild, SL Munch… - American Journal …, 2016 - journals.physiology.org
Preterm birth interrupts normal fetal growth with consequences for postnatal growth and
organ development. In preterm infants, many physiological deficits adapt and disappear with …
organ development. In preterm infants, many physiological deficits adapt and disappear with …
Human and bovine milk oligosaccharides elicit improved recognition memory concurrent with alterations in regional brain volumes and hippocampal mRNA …
Human milk contains a unique profile of oligosaccharides (OS) and preliminary evidence
suggests they impact brain development. The objective of this study was to assess the …
suggests they impact brain development. The objective of this study was to assess the …
The domestic piglet: an important model for investigating the neurodevelopmental consequences of early life insults
MS Conrad, RW Johnson - Annu. Rev. Anim. Biosci., 2015 - annualreviews.org
Insults in the prenatal and early postnatal period increase the risk for behavioral problems
later in life. One hypothesis is that pre-and postnatal stressors influence structural and …
later in life. One hypothesis is that pre-and postnatal stressors influence structural and …