Radiosynthesis, preclinical, and clinical positron emission tomography studies of carbon-11 labeled endogenous and natural exogenous compounds
The presence of positron emission tomography (PET) centers at most major hospitals
worldwide, along with the improvement of PET scanner sensitivity and the introduction of …
worldwide, along with the improvement of PET scanner sensitivity and the introduction of …
Effects of oral exposure to titanium dioxide nanoparticles on gut microbiota and gut-associated metabolism in vivo
Z Chen, S Han, D Zhou, S Zhou, G Jia - Nanoscale, 2019 - pubs.rsc.org
The antibacterial activity of titanium dioxide nanoparticles (TiO2 NPs) has been extensively
documented and applied to food packaging or environmental protection. Ingestion of TiO2 …
documented and applied to food packaging or environmental protection. Ingestion of TiO2 …
Implications of the dominant role of transporters in drug uptake by cells (supplementary material)
Drug entry into cells was previously believed to be via diffusion through the lipid bilayer of
the cell membrane, with the contribution to uptake by transporter proteins being of only …
the cell membrane, with the contribution to uptake by transporter proteins being of only …
Anti-apoptotic Bcl-2 family proteins disassemble ceramide channels
LJ Siskind, L Feinstein, T Yu, JS Davis, D Jones… - Journal of Biological …, 2008 - ASBMB
Early in mitochondria-mediated apoptosis, the mitochondrial outer membrane becomes
permeable to proteins that, when released into the cytosol, initiate the execution phase of …
permeable to proteins that, when released into the cytosol, initiate the execution phase of …
Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy
CA McLellan, BM Vincent, NV Solis… - Nature chemical …, 2018 - nature.com
The development of effective antifungal therapeutics remains a formidable challenge
because of the close evolutionary relationship between humans and fungi. Mitochondrial …
because of the close evolutionary relationship between humans and fungi. Mitochondrial …
NAGS, CPS1, and SLC25A13 (Citrin) at the Crossroads of Arginine and Pyrimidines Metabolism in Tumor Cells
M Owusu-Ansah, N Guptan, D Alindogan… - International Journal of …, 2023 - mdpi.com
Urea cycle enzymes and transporters collectively convert ammonia into urea in the liver.
Aberrant overexpression of carbamylphosphate synthetase 1 (CPS1) and SLC25A13 (citrin) …
Aberrant overexpression of carbamylphosphate synthetase 1 (CPS1) and SLC25A13 (citrin) …
Metabolomics reveals the renoprotective effect of n-butanol extract and amygdalin extract from Amygdalus mongolica in rats with renal fibrosis
W Bai, Q Liu, H Chang, Q Liu, C Gao, Y Bai… - Artificial Cells …, 2021 - Taylor & Francis
Renal fibrosis (RF) is a pathological process of progression from chronic kidney disease to
end-stage renal disease. Amygdalus mongolica is a traditional Chinese medicine, and our …
end-stage renal disease. Amygdalus mongolica is a traditional Chinese medicine, and our …
A Multi-Omic Mosaic Model of Acetaminophen Induced Alanine Aminotransferase Elevation
AA Monte, A Vest, JA Reisz, D Berninzoni… - Journal of Medical …, 2023 - Springer
Background Acetaminophen (APAP) is the most common cause liver injury following alcohol
in US patients. Predicting liver injury and subsequent hepatic regeneration in patients taking …
in US patients. Predicting liver injury and subsequent hepatic regeneration in patients taking …
Learning from yeast about mitochondrial carriers
M Mentel, P Chovančíková, I Zeman, P Polčic - Microorganisms, 2021 - mdpi.com
Mitochondria are organelles that play an important role in both energetic and synthetic
metabolism of eukaryotic cells. The flow of metabolites between the cytosol and …
metabolism of eukaryotic cells. The flow of metabolites between the cytosol and …
Insight into biological system responses in goldfish (Carassius auratus) to multiple doses of avermectin exposure by integrated 1H NMR-based metabolomics
MH Li, LY Ruan, Y Liu, HD Xu, T Chen… - Toxicology …, 2015 - academic.oup.com
The toxic effects of AVM were investigated using a teleost experimental model, the juvenile
goldfish (Carassius auratus). Goldfish were consecutively exposed to AVM for 7 days and …
goldfish (Carassius auratus). Goldfish were consecutively exposed to AVM for 7 days and …