Amikacin: uses, resistance, and prospects for inhibition

MS Ramirez, ME Tolmasky - Molecules, 2017 - mdpi.com
Aminoglycosides are a group of antibiotics used since the 1940s to primarily treat a broad
spectrum of bacterial infections. The primary resistance mechanism against these antibiotics …

Potential antibiotics for the treatment of neonatal sepsis caused by multidrug-resistant bacteria

CA Darlow, RMA da Costa, S Ellis, F Franceschi… - Pediatric Drugs, 2021 - Springer
Neonatal sepsis causes up to an estimated 680,000 deaths annually worldwide,
predominantly in low-and middle-income countries (LMICs). A significant and growing …

Amikacin combined with fosfomycin for treatment of neonatal sepsis in the setting of highly prevalent antimicrobial resistance

CA Darlow, F Docobo-Perez, N Farrington… - Antimicrobial Agents …, 2021 - Am Soc Microbiol
Antimicrobial resistance (particularly through extended-spectrum β-lactamase and
aminoglycoside-modifying enzyme production) in neonatal sepsis is a global problem …

[HTML][HTML] Antibiotics, Analgesic Sedatives, and Antiseizure Medications Frequently Used in Critically Ill Neonates: A Narrative Review

A Kontou, E Agakidou, I Chatziioannidis, W Chotas… - Children, 2024 - mdpi.com
Antibiotic, analgesic sedative, and antiseizure medications are among the most commonly
used medications in preterm/sick neonates, who are at high risk of nosocomial infections …

Assessment of flomoxef combined with amikacin in a hollow-fibre infection model for the treatment of neonatal sepsis in low-and middle-income healthcare settings

CA Darlow, L McEntee, A Johnson… - Journal of …, 2022 - academic.oup.com
Background Annual mortality from neonatal sepsis is an estimated 430 000–680 000 infants
globally, most of which occur in low-and middle-income countries (LMICs). The WHO …

Causative organisms and antimicrobial susceptibility in jaundiced infants with significant bacteriuria

LJ Chen, PJ Chen, SF Yang… - Journal of the Chinese …, 2022 - journals.lww.com
Background: Jaundice may be one of the first signs of urinary tract infection (UTI) in infants.
The most common pathogen is Escherichia coli. Currently recommended antibiotic treatment …

Ototoxic Drug Exposure and Hearing Loss in Neonates: A Scoping Review

S Rameshsankar, J Seethapathy… - American Journal of …, 2024 - pubs.asha.org
Purpose: This scoping review aims to map the effects of dosage levels, dosage intervals,
duration of exposure, and serum concentration levels of gentamicin, amikacin, vancomycin …

Drug Utilization Evaluation of Aminoglycosides, Gentamicin and Amikacin: A Retrospective study in pediatric patients at secondary care public hospital

K Chandrasekar, SJ Saju, BH Zechariah… - Research Journal of …, 2021 - indianjournals.com
Background: Antibiotics are potent drugs which are usually used in the treatment of bacterial
infections. Aminoglycosides are powerful, broad spectrum antibiotics that exhibits both gram …

[HTML][HTML] Antimicrobianos en neonatología. Parte I: Recomendaciones de dosificaciones basadas, en la más reciente evidencia en recién nacidos Comité Consultivo …

A Sandoval, M Aravena, F Cofré, L Delpiano… - Revista chilena de …, 2020 - SciELO Chile
Los antimicrobianos son los medicamentos más utilizados en los neonatos durante su
primer mes de vida cuando se encuentran en unidades neonatales, principalmente por el …

Review on Population Pharmacokinetics of Amikacin in Paediatrics.

K Chandrasekar, T Navaswetha… - Journal of Pure & …, 2022 - search.ebscohost.com
Amikacin is an aminoglycoside antibiotic with a broad-spectrum bacterial coverage that is
frequently utilized both as monotherapy and in combination with other antibiotics for severe …