Tracking placental development in health and disease
Pre-eclampsia and fetal growth restriction arise from disorders of placental development and
have some shared mechanistic features. Initiation is often rooted in the maldevelopment of a …
have some shared mechanistic features. Initiation is often rooted in the maldevelopment of a …
Roles of microRNAs in preeclampsia
Y Lv, C Lu, X Ji, Z Miao, W Long… - Journal of cellular …, 2019 - Wiley Online Library
Preeclampsia (PE) is a complex disorder that is characterized by hypertension and
proteinuria after the 20th week of pregnancy, and it causes most neonatal morbidity and …
proteinuria after the 20th week of pregnancy, and it causes most neonatal morbidity and …
Placental exosomes as early biomarker of preeclampsia: potential role of exosomal microRNAs across gestation
Context There is a need to develop strategies for early prediction of patients who will
develop preeclampsia (PE) to establish preventive strategies to reduce the prevalence and …
develop preeclampsia (PE) to establish preventive strategies to reduce the prevalence and …
[HTML][HTML] Epigenetic biomarkers in cardiovascular diseases
C Soler-Botija, C Gálvez-Montón… - Frontiers in genetics, 2019 - frontiersin.org
Cardiovascular diseases are the number one cause of death worldwide and greatly impact
quality of life and medical costs. Enormous effort has been made in research to obtain new …
quality of life and medical costs. Enormous effort has been made in research to obtain new …
[HTML][HTML] The prediction of gestational hypertension, preeclampsia and fetal growth restriction via the first trimester screening of plasma exosomal C19MC microRNAs
I Hromadnikova, L Dvorakova, K Kotlabova… - International journal of …, 2019 - mdpi.com
The aim of the study was to verify if quantification of placental specific C19MC microRNAs in
plasma exosomes would be able to differentiate during the early stages of gestation …
plasma exosomes would be able to differentiate during the early stages of gestation …
[HTML][HTML] MicroRNA–mRNA networks in pregnancy complications: A comprehensive downstream analysis of potential biomarkers
Pregnancy complications are a major cause of fetal and maternal morbidity and mortality in
humans. The majority of pregnancy complications initiate due to abnormal placental …
humans. The majority of pregnancy complications initiate due to abnormal placental …
[HTML][HTML] First trimester screening of circulating C19MC microRNAs and the evaluation of their potential to predict the onset of preeclampsia and IUGR
I Hromadnikova, K Kotlabova, K Ivankova, L Krofta - PLoS One, 2017 - journals.plos.org
Objectives A nested case control study of a longitudinal cohort comparing pregnant women
enrolled at 10 to 13 gestational weeks was carried out to evaluate risk assessment for …
enrolled at 10 to 13 gestational weeks was carried out to evaluate risk assessment for …
MicroRNAs: small molecules with a large impact on pre‐eclampsia
M Hemmatzadeh, N Shomali… - Journal of cellular …, 2020 - Wiley Online Library
As critical mediators in biological processes, microRNAs (miRNAs) which are small and
endogenous noncoding RNAs have been associated with disease progression, cell …
endogenous noncoding RNAs have been associated with disease progression, cell …
Pre-eclampsia predictive ability of maternal miR-125b: A clinical and experimental study
C Licini, C Avellini, E Picchiassi, E Mensà… - Translational …, 2021 - Elsevier
Pre-eclampsia (PE) is a systemic maternal syndrome affecting 2-8% of pregnancies
worldwide and involving poor placental perfusion and impaired blood supply to the foetus. It …
worldwide and involving poor placental perfusion and impaired blood supply to the foetus. It …
[HTML][HTML] Placenta-derived microRNAs in the pathophysiology of human pregnancy
P Xu, Y Ma, H Wu, YL Wang - Frontiers in cell and developmental …, 2021 - frontiersin.org
In placental mammals, reproductive success, and maternal-fetal health substantially depend
on a well-being placenta, the interface between the fetus and the mother. Disorders in …
on a well-being placenta, the interface between the fetus and the mother. Disorders in …