Since the discovery of chlorpromazine in the 1950's, antipsychotic drugs have been the
cornerstone of treatment of schizophrenia, and all attenuate dopamine transmission at the …

Currently, schizophrenia is considered a multifactorial disease. Over the past 50 years,
many investigators have considered the role of toxic free radicals in the etiology of …

Introduction: Postpartum depression is a common mental health problem that is associated
with maternal suffering. The aim of this double-blind clinical trial was to compare safety and …

Background The antidepressive effect of pioglitazone has been noted in patients with major
depressive disorder in absence of metabolic syndrome. This study was conducted to …

Objectives Recent research has focused on the inflammatory cascade as a key culprit in the
etiology of bipolar disorder. We hypothesized that celecoxib, via its anti‐inflammatory …

Patients with the HIV infection are at high risk for developing depression. The aim of this
study was to investigate the safety and efficacy of antidepressant effects of minocycline on …

Neovascular age-related macular degeneration (nAMD) is a leading cause of irreversible
visual impairment in the elderly. The current management of nAMD is limited and involves …

Recent evidences suggest that glutamatergic dysregulation implicated in neural plasticity
and cellular resilience may contribute to the pathophysiology of Major Depressive Disorder …

Objective: This is an investigation of minocycline efficacy and safety as an adjuvant to
risperidone in management of children with autism. Methods: Forty-six children with …

Cancer-related inflammation is an essential process in malignancies. Celecoxib, a
nonsteroidal anti-inflammatory drug that acts via the selective inhibition of cyclooxygenase …