Small RNAs, large networks: posttranscriptional regulons in gram-negative bacteria

K Papenfort, S Melamed - Annual review of microbiology, 2023 - annualreviews.org
Small regulatory RNA (sRNAs) are key mediators of posttranscriptional gene control in
bacteria. Assisted by RNA-binding proteins, a single sRNA often modulates the expression …

Small RNAs in bacteria and archaea: who they are, what they do, and how they do it

EGH Wagner, P Romby - Advances in genetics, 2015 - Elsevier
Small RNAs are ubiquitously present regulators in all kingdoms of life. Most bacterial and
archaeal small RNAs (sRNAs) act by antisense mechanisms on multiple target mRNAs …

Dual RNA-seq unveils noncoding RNA functions in host–pathogen interactions

AJ Westermann, KU Förstner, F Amman, L Barquist… - Nature, 2016 - nature.com
Bacteria express many small RNAs for which the regulatory roles in pathogenesis have
remained poorly understood due to a paucity of robust phenotypes in standard virulence …

Global mapping of small RNA-target interactions in bacteria

S Melamed, A Peer, R Faigenbaum-Romm, YE Gatt… - Molecular cell, 2016 - cell.com
Small RNAs (sRNAs) associated with the RNA chaperon protein Hfq are key
posttranscriptional regulators of gene expression in bacteria. Deciphering the sRNA-target …

Trans-Acting Small RNAs and Their Effects on Gene Expression in Escherichia coli and Salmonella enterica

J Hör, G Matera, J Vogel, S Gottesman, G Storz - EcoSal Plus, 2020 - Am Soc Microbiol
The last few decades have led to an explosion in our understanding of the major roles that
small regulatory RNAs (sRNAs) play in regulatory circuits and the responses to stress in …

Dual RNA-seq of pathogen and host

AJ Westermann, SA Gorski, J Vogel - Nature Reviews Microbiology, 2012 - nature.com
A comprehensive understanding of host–pathogen interactions requires a knowledge of the
associated gene expression changes in both the pathogen and the host. Traditional, probe …

An infection-relevant transcriptomic compendium for Salmonella enterica Serovar Typhimurium

C Kröger, A Colgan, S Srikumar, K Händler… - Cell host & …, 2013 - cell.com
Bacterial transcriptional networks consist of hundreds of transcription factors and thousands
of promoters. However, the true complexity of transcription in a bacterial pathogen and the …

Bacterial small RNA regulators: versatile roles and rapidly evolving variations

S Gottesman, G Storz - Cold Spring Harbor perspectives …, 2011 - cshperspectives.cshlp.org
Small RNA regulators (sRNAs) have been identified in a wide range of bacteria and found to
play critical regulatory roles in many processes. The major families of sRNAs include true …

[HTML][HTML] Regulatory RNAs in bacteria

LS Waters, G Storz - Cell, 2009 - cell.com
Bacteria possess numerous and diverse means of gene regulation using RNA molecules,
including mRNA leaders that affect expression in cis, small RNAs that bind to proteins or …

Cross-species RNA-seq for deciphering host–microbe interactions

AJ Westermann, J Vogel - Nature Reviews Genetics, 2021 - nature.com
The human body is constantly exposed to microorganisms, which entails manifold
interactions between human cells and diverse commensal or pathogenic bacteria. The …