[HTML][HTML] The role of chromatin during transcription
Chromatin structure imposes significant obstacles on all aspects of transcription that are
mediated by RNA polymerase II. The dynamics of chromatin structure are tightly regulated …
mediated by RNA polymerase II. The dynamics of chromatin structure are tightly regulated …
Functions of site-specific histone acetylation and deacetylation
MD Shahbazian, M Grunstein - Annu. Rev. Biochem., 2007 - annualreviews.org
Histone acetylation regulates many cellular processes, and specific acetylation marks, either
singly or in combination, produce distinct outcomes. For example, the acetylation pattern on …
singly or in combination, produce distinct outcomes. For example, the acetylation pattern on …
[HTML][HTML] Transcription shapes genome-wide histone acetylation patterns
BJE Martin, J Brind'Amour, A Kuzmin… - Nature …, 2021 - nature.com
Histone acetylation is a ubiquitous hallmark of transcription, but whether the link between
histone acetylation and transcription is causal or consequential has not been addressed …
histone acetylation and transcription is causal or consequential has not been addressed …
Link communities reveal multiscale complexity in networks
Networks have become a key approach to understanding systems of interacting objects,
unifying the study of diverse phenomena including biological organisms and human …
unifying the study of diverse phenomena including biological organisms and human …
[HTML][HTML] Histone acetylation: a switch between repressive and permissive chromatin
A Eberharter, PB Becker - EMBO reports, 2002 - embopress.org
The organization of eukaryotic chromatin has a major impact on all nuclear processes
involving DNA substrates. Gene expression is affected by the positioning of individual …
involving DNA substrates. Gene expression is affected by the positioning of individual …
Structure of the transcription coactivator SAGA
Gene transcription by RNA polymerase II is regulated by activator proteins that recruit the
coactivator complexes SAGA (Spt–Ada–Gcn5–acetyltransferase), and transcription factor IID …
coactivator complexes SAGA (Spt–Ada–Gcn5–acetyltransferase), and transcription factor IID …
Transcriptional Regulation in Saccharomyces cerevisiae: Transcription Factor Regulation and Function, Mechanisms of Initiation, and Roles of Activators and …
S Hahn, ET Young - Genetics, 2011 - academic.oup.com
Here we review recent advances in understanding the regulation of mRNA synthesis in
Saccharomyces cerevisiae. Many fundamental gene regulatory mechanisms have been …
Saccharomyces cerevisiae. Many fundamental gene regulatory mechanisms have been …
[HTML][HTML] Cooperation between complexes that regulate chromatin structure and transcription
Chromatin structure creates barriers for each step in eukaryotic transcription. Here we
discuss how the activities of two major classes of chromatin-modifying complexes, ATP …
discuss how the activities of two major classes of chromatin-modifying complexes, ATP …
Histone modifications in transcriptional regulation
SL Berger - Current opinion in genetics & development, 2002 - Elsevier
Covalent modifications of the amino termini of the core histones in nucleosomes have
important roles in gene regulation. Research in the past two years reveals these …
important roles in gene regulation. Research in the past two years reveals these …
[HTML][HTML] Bromodomain: an acetyl-lysine binding domain
L Zeng, MM Zhou - FEBS letters, 2002 - Elsevier
Bromodomains, an extensive family of evolutionarily conserved protein modules originally
found in proteins associated with chromatin and in nearly all nuclear histone …
found in proteins associated with chromatin and in nearly all nuclear histone …