Designing bioresponsive nanomaterials for intracellular self-assembly
Supramolecular assemblies are essential components of living organisms. Cellular
scaffolds, such as the cytoskeleton or the cell membrane, are formed via secondary …
scaffolds, such as the cytoskeleton or the cell membrane, are formed via secondary …
Fluorogenic probes for disease-relevant enzymes
Traditional biochemical methods for enzyme detection are mainly based on antibody-based
immunoassays, which lack the ability to monitor the spatiotemporal distribution and, in …
immunoassays, which lack the ability to monitor the spatiotemporal distribution and, in …
Enzymatic noncovalent synthesis
Enzymatic reactions and noncovalent (ie, supramolecular) interactions are two fundamental
nongenetic attributes of life. Enzymatic noncovalent synthesis (ENS) refers to a process …
nongenetic attributes of life. Enzymatic noncovalent synthesis (ENS) refers to a process …
Synthesizing biomaterials in living organisms
X Zhang, J Wang, Y Zhang, Z Yang, J Gao… - Chemical Society …, 2023 - pubs.rsc.org
Living organisms fabricate biomacromolecules such as DNA, RNA, and proteins by the self-
assembly process. The research on the mechanism of biomacromolecule formation also …
assembly process. The research on the mechanism of biomacromolecule formation also …
Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo
Directed self-assembly of small molecules in living systems could enable a myriad of
applications in biology and medicine, and already this has been used widely to synthesize …
applications in biology and medicine, and already this has been used widely to synthesize …
Orderly Self‐Assembly of Organic Fluorophores for Sensing and Imaging
Z Li, PZ Liang, TB Ren, L Yuan… - Angewandte Chemie, 2023 - Wiley Online Library
Fluorescence imaging utilizing traditional organic fluorophores is extensively applied in both
cellular and in vivo studies. However, it faces significant obstacles, such as low signal‐to …
cellular and in vivo studies. However, it faces significant obstacles, such as low signal‐to …
Facile syntheses of conjugated polymers for photothermal tumour therapy
P Chen, Y Ma, Z Zheng, C Wu, Y Wang… - Nature communications, 2019 - nature.com
Abstract Development of photothermal materials which are able to harness sunlight and
convert it to thermal energy seems attractive. Besides carbon-based nanomaterials …
convert it to thermal energy seems attractive. Besides carbon-based nanomaterials …
Peptides as targeting elements and tissue penetration devices for nanoparticles
E Ruoslahti - Advanced materials, 2012 - Wiley Online Library
The use of nanoparticles in medicine (nanomedicine) has recently become an intensely
studied field. Nanoparticles carrying drugs and imaging agents have already reached the …
studied field. Nanoparticles carrying drugs and imaging agents have already reached the …
Advances in aggregatable nanoparticles for tumor-targeted drug delivery
W Yu, M Shevtsov, X Chen, H Gao - Chinese chemical letters, 2020 - Elsevier
Recent days, aggregatable nanoparticles, which can specifically respond to certain stimulus,
have shown great potential in tumor-targeted drug delivery with prolonged retention and …
have shown great potential in tumor-targeted drug delivery with prolonged retention and …
Stimuli-Responsive Macrocyclization Scaffold Allows In Situ Self-Assembly of Radioactive Tracers for Positron Emission Tomography Imaging of Enzyme Activity
J Lin, D Gao, S Wang, G Lv, X Wang, C Lu… - Journal of the …, 2022 - ACS Publications
Target-enabled bioorthogonal reaction and self-assembly of a small-molecule probe into
supramolecules have shown promise for molecular imaging. In this paper, we report a new …
supramolecules have shown promise for molecular imaging. In this paper, we report a new …