Role of the gut–brain axis in energy and glucose metabolism
HR Wachsmuth, SN Weninger, FA Duca - Experimental & molecular …, 2022 - nature.com
The gastrointestinal tract plays a role in the development and treatment of metabolic
diseases. During a meal, the gut provides crucial information to the brain regarding …
diseases. During a meal, the gut provides crucial information to the brain regarding …
Function and mechanisms of enteroendocrine cells and gut hormones in metabolism
FM Gribble, F Reimann - Nature Reviews Endocrinology, 2019 - nature.com
Gut hormones have many key roles in the control of metabolism, as they target diverse
tissues involved in the control of intestinal function, insulin secretion, nutrient assimilation …
tissues involved in the control of intestinal function, insulin secretion, nutrient assimilation …
[HTML][HTML] A proximal-to-distal survey of healthy adult human small intestine and colon epithelium by single-cell transcriptomics
J Burclaff, RJ Bliton, KA Breau, MT Ok… - Cellular and molecular …, 2022 - Elsevier
Background & Aims Single-cell transcriptomics offer unprecedented resolution of tissue
function at the cellular level, yet studies analyzing healthy adult human small intestine and …
function at the cellular level, yet studies analyzing healthy adult human small intestine and …
[HTML][HTML] Anxiety, depression, and the microbiome: a role for gut peptides
The complex bidirectional communication between the gut and the brain is finely
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …
Ghrelin, CCK, GLP-1, and PYY (3–36): secretory controls and physiological roles in eating and glycemia in health, obesity, and after RYGB
The efficacy of Roux-en-Y gastric-bypass (RYGB) and other bariatric surgeries in the
management of obesity and type 2 diabetes mellitus and novel developments in …
management of obesity and type 2 diabetes mellitus and novel developments in …
Single-cell messenger RNA sequencing reveals rare intestinal cell types
Understanding the development and function of an organ requires the characterization of all
of its cell types. Traditional methods for visualizing and isolating subpopulations of cells are …
of its cell types. Traditional methods for visualizing and isolating subpopulations of cells are …
Feeding the microbiota-gut-brain axis: diet, microbiome, and neuropsychiatry
KV Sandhu, E Sherwin, H Schellekens, C Stanton… - Translational …, 2017 - Elsevier
The microbial population residing within the human gut represents one of the most densely
populated microbial niche in the human body with growing evidence showing it playing a …
populated microbial niche in the human body with growing evidence showing it playing a …
Identification of enteroendocrine regulators by real-time single-cell differentiation mapping
Homeostatic regulation of the intestinal enteroendocrine lineage hierarchy is a poorly
understood process. We resolved transcriptional changes during enteroendocrine …
understood process. We resolved transcriptional changes during enteroendocrine …
[HTML][HTML] Intestinal enteroendocrine lineage cells possess homeostatic and injury-inducible stem cell activity
Several cell populations have been reported to possess intestinal stem cell (ISC) activity
during homeostasis and injury-induced regeneration. Here, we explored inter-relationships …
during homeostasis and injury-induced regeneration. Here, we explored inter-relationships …
The physiology of the gastric parietal cell
AC Engevik, I Kaji, JR Goldenring - Physiological reviews, 2020 - journals.physiology.org
Parietal cells are responsible for gastric acid secretion, which aids in the digestion of food,
absorption of minerals, and control of harmful bacteria. However, a fine balance of activators …
absorption of minerals, and control of harmful bacteria. However, a fine balance of activators …