[HTML][HTML] Low dose ionizing radiation effects on the immune system

K Lumniczky, N Impens, G Armengol, S Candéias… - Environment …, 2021 - Elsevier
Ionizing radiation interacts with the immune system in many ways with a multiplicity that
mirrors the complexity of the immune system itself: namely the need to maintain a delicate …

Mechanisms of cancer cell death induction by paclitaxel: an updated review

S Zhao, Y Tang, R Wang, M Najafi - Apoptosis, 2022 - Springer
Chemoresistance of cancer cells is a major problem in treating cancer. Knowledge of how
cancer cells may die or resist cancer drugs is critical to providing certain strategies to …

Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma

KPL Bhat, V Balasubramaniyan, B Vaillant… - Cancer cell, 2013 - cell.com
Despite extensive study, few therapeutic targets have been identified for glioblastoma
(GBM). Here we show that patient-derived glioma sphere cultures (GSCs) that resemble …

Mechanisms of photoaging and cutaneous photocarcinogenesis, and photoprotective strategies with phytochemicals

R Bosch, N Philips, JA Suárez-Pérez, A Juarranz… - Antioxidants, 2015 - mdpi.com
Photoaging and photocarcinogenesis are primarily due to solar ultraviolet (UV) radiation,
which alters DNA, cellular antioxidant balance, signal transduction pathways, immunology …

Biological effects of radiation on cancer cells

J Wang, H Wang, H Qian - Military medical research, 2018 - Springer
With the development of radiotherapeutic oncology, computer technology and medical
imaging technology, radiation therapy has made great progress. Research on the impact …

Portrait of inflammatory response to ionizing radiation treatment

FM Di Maggio, L Minafra, GI Forte, FP Cammarata… - Journal of …, 2015 - Springer
Ionizing radiation (IR) activates both pro-and anti-proliferative signal pathways producing an
imbalance in cell fate decision. IR is able to regulate several genes and factors involved in …

Radioprotection and radiomitigation: from the bench to clinical practice

E Obrador, R Salvador, JI Villaescusa, JM Soriano… - Biomedicines, 2020 - mdpi.com
The development of protective agents against harmful radiations has been a subject of
investigation for decades. However, effective (ideal) radioprotectors and radiomitigators …

[PDF][PDF] Function of nuclear factor kappa B (NF-kB) in human diseases-a review

M Serasanambati, SR Chilakapati - South Indian Journal of …, 2016 - researchgate.net
Nuclear factor kappa B (NFkB) is a transcription factor that resides in the cytoplasm of every
cell and translocates to the nucleus when activated. Its activation is induced by a wide …

Nanodrug delivery in reversing multidrug resistance in cancer cells

S Kapse-Mistry, T Govender, R Srivastava… - Frontiers in …, 2014 - frontiersin.org
Different mechanisms in cancer cells become resistant to one or more chemotherapeutics is
known as multidrug resistance (MDR) which hinders chemotherapy efficacy. Potential …

p53 and breast cancer, an update

M Lacroix, RA Toillon, G Leclercq - Endocrine-related cancer, 2006 - erc.bioscientifica.com
p53 plays a key role in mediating cell response to various stresses, mainly by inducing or
repressing a number of genes involved in cell cycle arrest, senescence, apoptosis, DNA …