Endometriosis and risk of ovarian cancer: what do we know?

M Králíčková, AS Laganà, F Ghezzi… - Archives of gynecology and …, 2020 - Springer
Purpose Despite long and intensive research, endometriosis remains one of the leading
causes of morbidity among premenopausal women. The majority of endometriosis-related …

Targeting Nrf2 may reverse the drug resistance in ovarian cancer

D Li, X Hong, F Zhao, X Ci, S Zhang - Cancer Cell International, 2021 - Springer
Background Acquired resistance to therapeutic drugs has become an important issue in
treating ovarian cancer. Studies have shown that the prevalent chemotherapy resistance …

Mitochondrial fission causes cisplatin resistance under hypoxic conditions via ROS in ovarian cancer cells

Y Han, B Kim, U Cho, IS Park, SI Kim… - Oncogene, 2019 - nature.com
Mitochondria undergo fission and fusion continually for survival through the course of
cellular adaption processes in response to changes in the surrounding environment …

High throughput proteomics identifies a high-accuracy 11 plasma protein biomarker signature for ovarian cancer

S Enroth, M Berggrund, M Lycke, J Broberg… - Communications …, 2019 - nature.com
Ovarian cancer is usually detected at a late stage and the overall 5-year survival is only 30–
40%. Additional means for early detection and improved diagnosis are acutely needed. To …

Exosomal miR-99a-5p is elevated in sera of ovarian cancer patients and promotes cancer cell invasion by increasing fibronectin and vitronectin expression in …

A Yoshimura, K Sawada, K Nakamura, Y Kinose… - BMC cancer, 2018 - Springer
Background microRNAs (miRNAs) stably exist in circulating blood and are encapsulated in
extracellular vesicles such as exosomes. The aims of this study were to identify which …

[HTML][HTML] Role of biomarkers for early detection of ovarian cancer recurrence

P Giampaolino, V Foreste, L Della Corte… - Gland …, 2020 - ncbi.nlm.nih.gov
Ovarian cancer is frequently diagnosed at an advanced stage and a fraction of these
patients fail to respond to primary therapy and relapses in 70% of cases. On account of the …

Fucoidan Derived from Fucus vesiculosus Inhibits the Development of Human Ovarian Cancer via the Disturbance of Calcium Homeostasis, Endoplasmic Reticulum …

H Bae, JY Lee, C Yang, G Song, W Lim - Marine drugs, 2020 - mdpi.com
Marine organisms are sources of several natural compounds with potential clinical use.
However, only a few marine-based pharmaceuticals have been approved for use due to …

Aptamer biosensing based on metal enhanced fluorescence platform: A promising diagnostic tool

SM Sundaresan, SM Fothergill, TA Tabish… - Applied Physics …, 2021 - pubs.aip.org
Diagnosis of disease at an early, curable, and reversible stage allows more conservative
treatment and better patient outcomes. Fluorescence biosensing is a widely used method to …

Potential role of vaginal microbiota in ovarian cancer carcinogenesis, progression and treatment

X Zhao, Z Liu, T Chen - Pharmaceutics, 2023 - mdpi.com
Ovarian cancer represents one of the most challenging gynecologic cancers which still has
numerous unknowns on the underlying pathogenesis. In addition to the verified contributors …

Chrysophanol induces cell death and inhibits invasiveness via mitochondrial calcium overload in ovarian cancer cells

W Lim, Y An, C Yang, FW Bazer… - Journal of Cellular …, 2018 - Wiley Online Library
Chrysophanol is a phytochemical typically extracted from rhubarb. Similar to other extracts
from rhubarb, chrysophanol possesses anticancer activity against diverse cancerous cells …