Normal aging results in subtle changes both in ACTH and cortisol secretion. Most notable is
the general increase in mean daily serum cortisol levels in the elderly, without a noteworthy …

Objective Surgery is a stressor that can be categorized by duration and severity and induces
a systemic stress response that includes increased adrenal cortisol production. However …

Objective: This the second of two articles reviewing the scientific literature on the evaluation
and treatment of circadian rhythm sleep disorders (CRSDs), employing the methodology of …

To inform the future use of hair cortisol measurement, we have investigated influences of
potential confounding variables (natural hair colour, frequency of hair washes, age, sex, oral …

The systemic stress response triggered by surgical trauma is characterised by sterile
inflammation preceding metabolic and neuroendocrine dysregulation. However, the …

Disturbed sleep cycles are the principal cause of institutionalization in dementia, and
therefore represent a major clinical problem. They may arise from dysfunction within the …

Vital signs are objective measures of physiological function that are used to monitor acute
and chronic disease and thus serve as a basic communication tool about patient status. The …

Background We systematically reviewed and meta-analyzed the association of late-life
depression (LLD) with hippocampal volume (HCV) and total brain volume (TBV), and of …

Background Exposure to adverse childhood experiences (ACEs) may lead to stress-induced
upregulation of inflammatory and neuroendocrine processes. However, it remains unclear …

This study investigates the effect of acute psychosocial stress on serum concentrations of
DHEA and DHEA-S in healthy men and women. Twenty men and 19 women (age 30–50 …