[HTML][HTML] Benzimidazole-triazole hybrids as antimicrobial and antiviral agents: A systematic review

M Marinescu - Antibiotics, 2023 - mdpi.com
Bacterial infections have attracted the attention of researchers in recent decades, especially
due to the special problems they have faced, such as their increasing diversity and …

[HTML][HTML] A review on metal complexes and its anti-cancer activities: Recent updates from in vivo studies

S Adhikari, P Nath, A Das, A Datta, N Baildya… - Biomedicine & …, 2024 - Elsevier
Research into cancer therapeutics has uncovered various potential medications based on
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …

Recent advances in the anticancer applications of benzimidazole derivatives

M Mavvaji, S Akkoc - ChemistrySelect, 2023 - Wiley Online Library
Cancer, one of the most deadly diseases worldwide, is still a crucial challenge to human
well‐being. Hence, the design and development of modern protocols to cure diverse kinds …

Exploration of Remarkably Potential Multitarget-Directed N-Alkylated-2-(substituted phenyl)-1H-benzimidazole Derivatives as Antiproliferative, Antifungal, and …

NKN Phan, TKC Huynh, HP Nguyen, QT Le… - ACS …, 2023 - ACS Publications
Improving lipophilicity for drugs to penetrate the lipid membrane and decreasing bacterial
and fungal coinfections for patients with cancer pose challenges in the drug development …

In-silico design, pharmacophore-based screening, and molecular docking studies reveal that benzimidazole-1,2,3-triazole hybrids as novel EGFR inhibitors targeting …

S Kumar, I Ali, F Abbas, A Rana, S Pandey… - Journal of …, 2023 - Taylor & Francis
Lung cancer is a complex and heterogeneous disease, which has been associated with
various molecular alterations, including the overexpression and mutations of the epidermal …

[HTML][HTML] Structure–Activity Relationships in NHC–Silver Complexes as Antimicrobial Agents

L Ronga, M Varcamonti, D Tesauro - Molecules, 2023 - mdpi.com
Silver has a long history of antimicrobial activity and received an increasing interest in last
decades owing to the rise in antimicrobial resistance. The major drawback is the limited …

Aminopyridone-linked benzimidazoles: a fragment-based drug design for the development of CDK9 inhibitors

EM Husseiny, HS Abulkhair, SSA El-Hddad… - Future Medicinal …, 2023 - Taylor & Francis
Aim: A fragment-based design and synthesis of three novel series of aminopyridone-linked
benzimidazoles as potential anticancer candidates with significant CDK9 inhibition was …

Recent advances in nitrogen-containing heterocyclic compounds as receptor tyrosine kinase inhibitors for the treatment of cancer: biological activity and structural …

KT Jha, A Shome, PA Chawla - Bioorganic Chemistry, 2023 - Elsevier
Erratic cell proliferation is the initial symptom of cancer, which can eventually metastasize to
other organs. Before cancer becomes metastatic, its spread is triggered by pro-angiogenic …

Antimicrobial and antibiofilm activities and bovine serum albumin binding properties of benzimidazolium derivative NHC salts and their Ag (I)‐NHC complexes

C Çelik, E Üstün, N Şahin… - Applied Organometallic …, 2022 - Wiley Online Library
Benzimidazole type N‐heterocyclic carbene molecules and their metal complexes have well‐
known biological activity. Elemental silver and silver complexes also have antibacterial and …

[HTML][HTML] Computational and theoretical chemistry of newly synthesized and characterized 2,2'-(5,5'-(1,4-phenylene)bis(1H-tetrazole-5,1-diyl))bis-N-acetamides

SA Ejaz, A Farid, S Zargar, PA Channar, M Aziz… - BMC chemistry, 2023 - Springer
Energetic heterocycles, including pyridines, triazoles, and tetrazoles, exhibit greater density,
heats of formation, and oxygen balance compared to their carbocyclic counterparts, making …