[HTML][HTML] Benzimidazole-triazole hybrids as antimicrobial and antiviral agents: A systematic review
M Marinescu - Antibiotics, 2023 - mdpi.com
Bacterial infections have attracted the attention of researchers in recent decades, especially
due to the special problems they have faced, such as their increasing diversity and …
due to the special problems they have faced, such as their increasing diversity and …
[HTML][HTML] A review on metal complexes and its anti-cancer activities: Recent updates from in vivo studies
Research into cancer therapeutics has uncovered various potential medications based on
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …
Recent advances in the anticancer applications of benzimidazole derivatives
Cancer, one of the most deadly diseases worldwide, is still a crucial challenge to human
well‐being. Hence, the design and development of modern protocols to cure diverse kinds …
well‐being. Hence, the design and development of modern protocols to cure diverse kinds …
Exploration of Remarkably Potential Multitarget-Directed N-Alkylated-2-(substituted phenyl)-1H-benzimidazole Derivatives as Antiproliferative, Antifungal, and …
NKN Phan, TKC Huynh, HP Nguyen, QT Le… - ACS …, 2023 - ACS Publications
Improving lipophilicity for drugs to penetrate the lipid membrane and decreasing bacterial
and fungal coinfections for patients with cancer pose challenges in the drug development …
and fungal coinfections for patients with cancer pose challenges in the drug development …
In-silico design, pharmacophore-based screening, and molecular docking studies reveal that benzimidazole-1,2,3-triazole hybrids as novel EGFR inhibitors targeting …
Lung cancer is a complex and heterogeneous disease, which has been associated with
various molecular alterations, including the overexpression and mutations of the epidermal …
various molecular alterations, including the overexpression and mutations of the epidermal …
[HTML][HTML] Structure–Activity Relationships in NHC–Silver Complexes as Antimicrobial Agents
L Ronga, M Varcamonti, D Tesauro - Molecules, 2023 - mdpi.com
Silver has a long history of antimicrobial activity and received an increasing interest in last
decades owing to the rise in antimicrobial resistance. The major drawback is the limited …
decades owing to the rise in antimicrobial resistance. The major drawback is the limited …
Aminopyridone-linked benzimidazoles: a fragment-based drug design for the development of CDK9 inhibitors
EM Husseiny, HS Abulkhair, SSA El-Hddad… - Future Medicinal …, 2023 - Taylor & Francis
Aim: A fragment-based design and synthesis of three novel series of aminopyridone-linked
benzimidazoles as potential anticancer candidates with significant CDK9 inhibition was …
benzimidazoles as potential anticancer candidates with significant CDK9 inhibition was …
Recent advances in nitrogen-containing heterocyclic compounds as receptor tyrosine kinase inhibitors for the treatment of cancer: biological activity and structural …
Erratic cell proliferation is the initial symptom of cancer, which can eventually metastasize to
other organs. Before cancer becomes metastatic, its spread is triggered by pro-angiogenic …
other organs. Before cancer becomes metastatic, its spread is triggered by pro-angiogenic …
Antimicrobial and antibiofilm activities and bovine serum albumin binding properties of benzimidazolium derivative NHC salts and their Ag (I)‐NHC complexes
Benzimidazole type N‐heterocyclic carbene molecules and their metal complexes have well‐
known biological activity. Elemental silver and silver complexes also have antibacterial and …
known biological activity. Elemental silver and silver complexes also have antibacterial and …
[HTML][HTML] Computational and theoretical chemistry of newly synthesized and characterized 2,2'-(5,5'-(1,4-phenylene)bis(1H-tetrazole-5,1-diyl))bis-N-acetamides
Energetic heterocycles, including pyridines, triazoles, and tetrazoles, exhibit greater density,
heats of formation, and oxygen balance compared to their carbocyclic counterparts, making …
heats of formation, and oxygen balance compared to their carbocyclic counterparts, making …