[HTML][HTML] Mechanisms of host manipulation by Neisseria gonorrhoeae
Neisseria gonorrhoeae (also known as gonococcus) has been causing gonorrhoea in
humans since ancient Egyptian times. Today, global gonorrhoea infections are rising at an …
humans since ancient Egyptian times. Today, global gonorrhoea infections are rising at an …
In vitro modelling of the physiological and diseased female reproductive system
A Stejskalova, H Vankelecom, M Sourouni, MY Ho… - Acta biomaterialia, 2021 - Elsevier
The maladies affecting the female reproductive tract (FRT) range from infections to
endometriosis to carcinomas. In vitro models of the FRT play an increasingly important role …
endometriosis to carcinomas. In vitro models of the FRT play an increasingly important role …
[HTML][HTML] Neisseria gonorrhoeae co-opts C4b-binding protein to enhance complement-independent survival from neutrophils
Neisseria gonorrhoeae (Gc) is a human-specific pathogen that causes the sexually
transmitted infection gonorrhea. Gc survives in neutrophil-rich gonorrheal secretions, and …
transmitted infection gonorrhea. Gc survives in neutrophil-rich gonorrheal secretions, and …
Variable expression of opa proteins by Neisseria gonorrhoeae influences bacterial association and phagocytic killing by human neutrophils
AM Alcott, LM Werner, CM Baiocco… - Journal of …, 2022 - Am Soc Microbiol
Neisseria gonorrhoeae infection is characterized by local and abundant recruitment of
neutrophils. Despite neutrophils' antimicrobial activities, viable N. gonorrhoeae is recovered …
neutrophils. Despite neutrophils' antimicrobial activities, viable N. gonorrhoeae is recovered …
[PDF][PDF] Neisseria gonorrhoeae blocks epithelial exfoliation by nitric-oxide-mediated metabolic cross talk to promote colonization in mice
P Muenzner, CR Hauck - Cell host & microbe, 2020 - cell.com
Several pathogens suppress exfoliation, a key defense of epithelia against microbial
colonization. Common among these pathogens, exemplified by Neisseria gonorrhoeae, is …
colonization. Common among these pathogens, exemplified by Neisseria gonorrhoeae, is …
[HTML][HTML] Gonococcal OMV-delivered PorB induces epithelial cell mitophagy
S Gao, L Gao, D Yuan, X Lin, S van der Veen - Nature Communications, 2024 - nature.com
The bacterial pathogen Neisseria gonorrhoeae is able to invade epithelial cells and survive
intracellularly. During this process, it secretes outer membrane vesicles (OMVs), however …
intracellularly. During this process, it secretes outer membrane vesicles (OMVs), however …
[HTML][HTML] Pharmacokinetic/pharmacodynamic considerations for new and current therapeutic drugs for uncomplicated gonorrhoea—challenges and opportunities
U Theuretzbacher, L Barbee, K Connolly… - Clinical Microbiology …, 2020 - Elsevier
Background Increasing multidrug resistance rates in Neisseria gonorrhoeae have raised
concerns and an urgent call for new antibiotics for treatment of gonorrhoea. Several …
concerns and an urgent call for new antibiotics for treatment of gonorrhoea. Several …
[HTML][HTML] Intimate relations: molecular and immunologic interactions between Neisseria gonorrhoeae and HIV-1
While the global incidence of human immunodeficiency virus (HIV-1) remains well above
UNAIDS targets, sexual transmission HIV is surprisingly inefficient. A variety of host, viral …
UNAIDS targets, sexual transmission HIV is surprisingly inefficient. A variety of host, viral …
[HTML][HTML] Engagement of CEACAM1 by Helicobacter pylori HopQ Is Important for the Activation of Non-Canonical NF-κB in Gastric Epithelial Cells
K Taxauer, Y Hamway, A Ralser, A Dietl, K Mink… - Microorganisms, 2021 - mdpi.com
The gastric pathogen Helicobacter pylori infects half of the world's population and is a major
risk factor for gastric cancer development. In order to attach to human gastric epithelial cells …
risk factor for gastric cancer development. In order to attach to human gastric epithelial cells …
[HTML][HTML] Tissue Models for Neisseria gonorrhoeae Research—From 2D to 3D
M Heydarian, E Rühl, R Rawal… - Frontiers in Cellular and …, 2022 - frontiersin.org
Neisseria gonorrhoeae is a human-specific pathogen that causes gonorrhea, the second
most common sexually transmitted infection worldwide. Disease progression, drug …
most common sexually transmitted infection worldwide. Disease progression, drug …