Wireless and battery-free technologies for neuroengineering

SM Won, L Cai, P Gutruf, JA Rogers - Nature Biomedical Engineering, 2023 - nature.com
Tethered and battery-powered devices that interface with neural tissues can restrict natural
motions and prevent social interactions in animal models, thereby limiting the utility of these …

Autism spectrum disorder: neurodevelopmental risk factors, biological mechanism, and precision therapy

L Wang, B Wang, C Wu, J Wang, M Sun - International journal of …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a heterogeneous, behaviorally defined
neurodevelopmental disorder. Over the past two decades, the prevalence of autism …

Bacterial sensing via neuronal Nod2 regulates appetite and body temperature

I Gabanyi, G Lepousez, R Wheeler, A Vieites-Prado… - Science, 2022 - science.org
Gut bacteria influence brain functions and metabolism. We investigated whether this
influence can be mediated by direct sensing of bacterial cell wall components by brain …

[HTML][HTML] Mechanisms underlying microbial-mediated changes in social behavior in mouse models of autism spectrum disorder

M Sgritta, SW Dooling, SA Buffington, EN Momin… - Neuron, 2019 - cell.com
Currently, there are no medications that effectively treat the core symptoms of Autism
Spectrum Disorder (ASD). We recently found that the bacterial species Lactobacillus (L.) …

Fear balance is maintained by bodily feedback to the insular cortex in mice

AS Klein, N Dolensek, C Weiand, N Gogolla - Science, 2021 - science.org
How does the brain maintain fear within an adaptive range? We found that the insular cortex
acts as a state-dependent regulator of fear that is necessary to establish an equilibrium …

Social trauma engages lateral septum circuitry to occlude social reward

L Li, R Durand-de Cuttoli, AV Aubry, CJ Burnett… - Nature, 2023 - nature.com
In humans, traumatic social experiences can contribute to psychiatric disorders. It is
suggested that social trauma impairs brain reward function such that social behaviour is no …

Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors

T Patriarchi, JR Cho, K Merten, MW Howe, A Marley… - Science, 2018 - science.org
INTRODUCTION Neuromodulators, such as dopamine, norepinephrine, or serotonin, exert
powerful control over neural circuit dynamics that give rise to diverse neural function and …

[HTML][HTML] Responses and functions of dopamine in nucleus accumbens core during social behaviors

B Dai, F Sun, X Tong, Y Ding, A Kuang, T Osakada… - Cell reports, 2022 - cell.com
Social behaviors are among the most important motivated behaviors. How dopamine (DA),
a" reward" signal, releases during social behaviors has been a topic of interest for decades …

Deep posteromedial cortical rhythm in dissociation

S Vesuna, IV Kauvar, E Richman, F Gore, T Oskotsky… - Nature, 2020 - nature.com
Advanced imaging methods now allow cell-type-specific recording of neural activity across
the mammalian brain, potentially enabling the exploration of how brain-wide dynamical …

Near-infrared deep brain stimulation via upconversion nanoparticle–mediated optogenetics

S Chen, AZ Weitemier, X Zeng, L He, X Wang, Y Tao… - Science, 2018 - science.org
Optogenetics has revolutionized the experimental interrogation of neural circuits and holds
promise for the treatment of neurological disorders. It is limited, however, because visible …