Aptamer-based point-of-care devices: Emerging technologies and integration of computational methods

Y Aslan, M Atabay, HK Chowdhury, I Göktürk, Y Saylan… - Biosensors, 2023 - mdpi.com
Recent innovations in point-of-care (POC) diagnostic technologies have paved a critical
road for the improved application of biomedicine through the deployment of accurate and …

Advances in optical aptasensors for early detection and diagnosis of various cancer types

Q Zahra, QA Khan, Z Luo - Frontiers in Oncology, 2021 - frontiersin.org
Cancer is a life-threatening concern worldwide. Sensitive and early-stage diagnostics of
different cancer types can make it possible for patients to get through the best available …

Aptamer blocking strategy inhibits SARS‐CoV‐2 virus infection

M Sun, S Liu, X Wei, S Wan, M Huang… - Angewandte Chemie …, 2021 - Wiley Online Library
The COVID‐19 pandemic caused by SARS‐CoV‐2 is threating global health. Inhibiting
interaction of the receptor‐binding domain of SARS‐CoV‐2 S protein (SRBD) and human …

Cobalt metal-organic framework modified carbon cloth/paper hybrid electrochemical button-sensor for nonenzymatic glucose diagnostics

X Wei, J Guo, H Lian, X Sun, B Liu - Sensors and Actuators B: Chemical, 2021 - Elsevier
In the growing pandemic, family healthcare is widely concerned with the increase of medical
self-diagnosis away from the hospital. A cobalt metal-organic framework modified carbon …

An electrochemical biosensor based on network-like DNA nanoprobes for detection of mesenchymal circulating tumor cells

Y Peng, S Ou, M Li, Z Hu, Z Zeng, N Feng - Biosensors and Bioelectronics, 2023 - Elsevier
The identification and detection of mesenchymal circulating tumor cells (mCTCs) is
important for early warning of tumor metastasis. The majority of conventional detection …

Facile, rapid and efficient isolation of circulating tumor cells using aptamer-targeted magnetic nanoparticles integrated with a microfluidic device

AA Kajani, L Rafiee, M Samandari, MA Mehrgardi… - RSC …, 2022 - pubs.rsc.org
Facile and sensitive detection and isolation of circulating tumor cells (CTCs) was achieved
using the aptamer-targeted magnetic nanoparticles (Apt-MNPs) in conjugation with a …

Magnetic bead-based electrochemical and colorimetric assays of circulating tumor cells with boronic acid derivatives as the recognition elements and signal probes

N Xia, D Wu, H Yu, W Sun, X Yi, L Liu - Talanta, 2021 - Elsevier
Simple, sensitive and rapid detection of circulating tumor cells (CTCs) is of great importance
for early diagnosis and therapy of cancers. Overexpression of sugar units on cell surface is …

Electrochemical Biosensors Based on Micro‐fabricated Devices for Point‐of‐Care Testing: A Review

Y Zhang, N Zhou - Electroanalysis, 2022 - Wiley Online Library
Point‐of‐care testing (POCT) is becoming a hot research topic that allows rapid, on‐site, and
non‐professional measurements outside the central laboratory. The micro‐fabricated …

Molecular Crowding Modulates SARS‐CoV‐2 Aptamer Affinity

T Song, M Sun, J Zhang, Y Lu, S Wan, C Yang… - Small …, 2023 - Wiley Online Library
SARS‐CoV‐2 aptamer is a favorable candidate for the recognition and detection of SARS‐
CoV‐2, owing to its small size and easy synthesis. However, the issue of compromised …

Construction of a Mass-Tagged Oligo Probe Set for Revealing Protein Ratiometric Relationship Associated with EGFR–HER2 Heterodimerization in Living Cells

X Li, B Sun, J Zhu, M Qian, Y Chen - Analytical Chemistry, 2022 - ACS Publications
Protein dimerization, as the most common form of protein–protein interaction, can manifest
more significant roles in cellular signaling than individual monomers. For example …