1, 1, 1, 3, 3, 3-Hexafluoroisopropanol (HFIP) is a polar, strongly hydrogen bond-donating
solvent that has found numerous uses in organic synthesis due to its ability to stabilize ionic …

Fluorinated alcohols have been widely used in the synthetic organic chemistry over the past
decades. The unique properties such as the strong hydrogen‐bonding donor ability and low …

Axial chirality widely exists in natural products, pharmaceutical compounds, and other
functional molecules; these axially chiral compounds also find wide utility as catalysts or …

The construction of N–N axially chiral motifs is an important research topic, owing to their
wide occurrence in natural products, pharmaceuticals and chiral ligands. One efficient …

We present herein an unprecedented stereoselective synthesis of bridged biaryls with
defined axial and central chirality from readily available starting materials. This N …

N-Heterocyclic carbene (NHC) organocatalysis has been recognized as a powerful synthetic
strategy for the construction of a wide variety of medicinally and biologically important …

Sulfur-containing tetrasubstituted carbon stereocenters are widely present in natural
products, drugs, and biologically active compounds. Catalytic enantioselective construction …

Sulfur (VI) fluoride exchange (SuFEx) click chemistry provides a powerful tool for the rapid
assembly of modular connections. Herein, we report an organocatalytic SuFEx reaction of …

The synthesis of enantiomerically pure 1, 3‐mercaptoalkanol volatile sulfur compounds
through a one‐pot photo‐biocatalytic cascade reaction is described. Two new KRED …

N-Heterocyclic carbenes (NHCs) are versatile species that figure prominently as catalysts.
Despite their widespread use in organocatalysis, studies of the relationship between the …