The importance of microfluidics for the preparation of nanoparticles as advanced drug delivery systems
JP Martins, G Torrieri, HA Santos - Expert opinion on drug delivery, 2018 - Taylor & Francis
Introduction: Nanoparticles are anticipated to overcome persistent challenges in efficient
drug delivery, but the limitations associated with conventional methods of preparation are …
drug delivery, but the limitations associated with conventional methods of preparation are …
Theranostic design of angiopep-2 conjugated hyaluronic acid nanoparticles (Thera-ANG-cHANPs) for dual targeting and boosted imaging of glioma cells
A Costagliola di Polidoro, G Zambito, J Haeck… - Cancers, 2021 - mdpi.com
Simple Summary Glioblastoma multiforme is the most aggressive malignant brain tumor with
poor patient prognosis. The presence of the blood-brain barrier and the complex tumor …
poor patient prognosis. The presence of the blood-brain barrier and the complex tumor …
A microfluidic platform to design multimodal PEG-crosslinked hyaluronic acid nanoparticles (PEG-cHANPs) for diagnostic applications
The combination of different imaging modalities can allow obtaining simultaneously
morphological and functional information providing a more accurate diagnosis. This …
morphological and functional information providing a more accurate diagnosis. This …
On-chip control over polyelectrolyte–surfactant complexation in nonequilibrium microfluidic confinement
A Bezrukov, Y Galyametdinov - Polymers, 2022 - mdpi.com
The goal of this work is to classify and quantify the factors that govern polyelectrolyte–
surfactant complexation in microfluidic confinement and optimize the designs and operating …
surfactant complexation in microfluidic confinement and optimize the designs and operating …
Insulin Activation Mediated by Uptake Mechanisms: A Comparison of the Behavior between Polymer Nanoparticles and Extracellular Vesicles in 3D Liver Tissues
A Costagliola di Polidoro, Z Baghbantarghdari… - …, 2023 - ACS Publications
In this work, we compare the role of two different uptake mechanisms in the effectiveness of
a nanoformulated drug, specifically insulin. Insulin is activated by interacting with insulin …
a nanoformulated drug, specifically insulin. Insulin is activated by interacting with insulin …
Activation and switching of supramolecular chemical signals in multi-output microfluidic devices
A Bezrukov, Y Galyametdinov - Micromachines, 2022 - mdpi.com
In this study, we report on the developing of a continuous microfluidic reaction device that
allows selective activation of polyelectrolyte-surfactant chemical signals in microflows and …
allows selective activation of polyelectrolyte-surfactant chemical signals in microflows and …
Targeting nanostrategies for imaging of atherosclerosis
A Costagliola di Polidoro, A Grassia… - Contrast Media & …, 2021 - Wiley Online Library
Despite the progress in cardiovascular research, atherosclerosis still represents the main
cause of death worldwide. Clinically, the diagnosis of Atherosclerotic Cardiovascular …
cause of death worldwide. Clinically, the diagnosis of Atherosclerotic Cardiovascular …
[HTML][HTML] Water-mediated nanostructures for enhanced MRI: impact of water dynamics on relaxometric properties of Gd-DTPA
F De Sarno, AM Ponsiglione, M Russo, AM Grimaldi… - Theranostics, 2019 - ncbi.nlm.nih.gov
Recently, rational design of a new class of contrast agents (CAs), based on biopolymers
(hydrogels), have received considerable attention in Magnetic Resonance Imaging (MRI) …
(hydrogels), have received considerable attention in Magnetic Resonance Imaging (MRI) …
Glycosaminoglycans and contrast agents: The role of hyaluronic acid as MRI contrast enhancer
AM Ponsiglione, M Russo, E Torino - Biomolecules, 2020 - mdpi.com
A comprehensive understanding of the behaviour of Glycosaminoglycans (GAGs) combined
with imaging or therapeutic agents can be a key factor for the rational design of drug delivery …
with imaging or therapeutic agents can be a key factor for the rational design of drug delivery …
HA PEGylated filler in association with an infrared energy device for the treatment of facial skin aging: 150 day follow-up data report
Background: The face is the area most exposed to the normal course of skin aging, both
intrinsically and extrinsically. The aim of the study was to evaluate the cellular and clinical …
intrinsically and extrinsically. The aim of the study was to evaluate the cellular and clinical …