Three-dimensional spheroids as in vitro preclinical models for cancer research

B Pinto, AC Henriques, PMA Silva, H Bousbaa - Pharmaceutics, 2020 - mdpi.com
Most cancer biologists still rely on conventional two-dimensional (2D) monolayer culture
techniques to test in vitro anti-tumor drugs prior to in vivo testing. However, the vast majority …

Alginate-based biomaterials for regenerative medicine applications

J Sun, H Tan - Materials, 2013 - mdpi.com
Alginate is a natural polysaccharide exhibiting excellent biocompatibility and
biodegradability, having many different applications in the field of biomedicine. Alginate is …

Multicomponent polysaccharide alginate-based bioinks

CC Piras, DK Smith - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
3D-Bioprinting has seen a rapid expansion in the last few years, with an increasing number
of reported bioinks. Alginate is a natural biopolymer that forms hydrogels by ionic cross …

Microfluidic spinning of micro-and nano-scale fibers for tissue engineering

Y Jun, E Kang, S Chae, SH Lee - Lab on a Chip, 2014 - pubs.rsc.org
Microfluidic technologies have recently been shown to hold significant potential as novel
tools for producing micro-and nano-scale structures for a variety of applications in tissue …

[HTML][HTML] A photocurable hybrid chitosan/acrylamide bioink for DLP based 3D bioprinting

Y He, F Wang, X Wang, J Zhang, D Wang, X Huang - Materials & Design, 2021 - Elsevier
Chitosan-based hydrogel has been widely used in the field of tissue engineering due to its
favorable biocompatibility and good biodegradability. However, this kind of hydrogel …

Immunological and technical considerations in application of alginate-based microencapsulation systems

GA Paredes Juárez, M Spasojevic, MM Faas… - … in bioengineering and …, 2014 - frontiersin.org
Islets encapsulated in immunoprotective microcapsules are being proposed as an
alternative for insulin therapy for treatment of type 1 diabetes. Many materials for producing …

Generation and functional assessment of 3D multicellular spheroids in droplet based microfluidics platform

P Sabhachandani, V Motwani, N Cohen, S Sarkar… - Lab on a Chip, 2016 - pubs.rsc.org
Here we describe a robust, microfluidic technique to generate and analyze 3D tumor
spheroids, which resembles tumor microenvironment and can be used as a more effective …

[图书][B] Bioprinting: principles and applications

CK Chua, WY Yeong - 2015 - uvic.ca
This course shows the ways that 3D printing and 3D bioprinting are revolutionizing the
available treatments available for medical needs. 3D bioprinting requires collaboration …

Generation and manipulation of hydrogel microcapsules by droplet-based microfluidics for mammalian cell culture

H Huang, Y Yu, Y Hu, X He, OB Usta, ML Yarmush - Lab on a Chip, 2017 - pubs.rsc.org
Hydrogel microcapsules provide miniaturized and biocompatible niches for three-
dimensional (3D) in vitro cell culture. They can be easily generated by droplet-based …

Review on multicomponent hydrogel bioinks based on natural biomaterials for bioprinting 3D liver tissues

D Kim, M Kim, J Lee, J Jang - Frontiers in bioengineering and …, 2022 - frontiersin.org
Three-dimensional (3D)-printed in vitro tissue models have been used in various biomedical
fields owing to numerous advantages such as enhancements in cell response and …