Validity of the Symbol Digit Modalities Test as a cognition performance outcome measure for multiple sclerosis

RHB Benedict, J DeLuca, G Phillips… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Cognitive and motor performance measures are commonly employed in multiple sclerosis
(MS) research, particularly when the purpose is to determine the efficacy of treatment. The …

Treatment and management of cognitive dysfunction in patients with multiple sclerosis

J DeLuca, ND Chiaravalloti, BM Sandroff - Nature Reviews Neurology, 2020 - nature.com
Cognitive impairment is a common and devastating manifestation of multiple sclerosis (MS).
Although disease-modifying therapies have been efficacious for reducing relapse rates in …

SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery

JJ Frere, RA Serafini, KD Pryce, M Zazhytska… - Science translational …, 2022 - science.org
The host response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection can result in prolonged pathologies collectively referred to as post-acute sequalae …

Deep gray matter volume loss drives disability worsening in multiple sclerosis

A Eshaghi, F Prados, WJ Brownlee… - Annals of …, 2018 - Wiley Online Library
Objective Gray matter (GM) atrophy occurs in all multiple sclerosis (MS) phenotypes. We
investigated whether there is a spatiotemporal pattern of GM atrophy that is associated with …

Predicting cognitive decline in multiple sclerosis: a 5-year follow-up study

AJC Eijlers, Q van Geest, I Dekker, MD Steenwijk… - Brain, 2018 - academic.oup.com
Cognitive decline is common in multiple sclerosis and strongly affects overall quality of life.
Despite the identification of cross-sectional MRI correlates of cognitive impairment …

Depressive symptoms, anxiety and cognitive impairment: emerging evidence in multiple sclerosis

M Margoni, P Preziosa, MA Rocca, M Filippi - Translational Psychiatry, 2023 - nature.com
Neuropsychiatric abnormalities may be broadly divided in two categories: disorders of
mood, affect, and behavior and abnormalities affecting cognition. Among these conditions …

Multiple sclerosis and cognition: synaptic failure and network dysfunction

M Di Filippo, E Portaccio, A Mancini… - Nature Reviews …, 2018 - nature.com
Cognitive impairment is increasingly recognized to be a core feature of multiple sclerosis
(MS), with important implications for the everyday life of individuals with MS and for disease …

Neurodegeneration in multiple sclerosis and neuromyelitis optica

I Kawachi, H Lassmann - Journal of Neurology, Neurosurgery & …, 2017 - jnnp.bmj.com
Multiple sclerosis (MS) and neuromyelitis optica (NMO) are autoimmune demyelinating
diseases of the central nervous system (CNS), having distinct immunological and …

[HTML][HTML] Neuropsychiatric symptoms of multiple sclerosis: state of the art

C Silveira, R Guedes, D Maia, R Curral… - Psychiatry …, 2019 - ncbi.nlm.nih.gov
Multiple Sclerosis (MS) is a chronic disabling neuroinflammatory disease. Psychiatric
manifestations have a high prevalence in MS patients and may worsen the illness …

Injured brains and adaptive networks: the benefits and costs of hyperconnectivity

FG Hillary, JH Grafman - Trends in cognitive sciences, 2017 - cell.com
A common finding in human functional brain-imaging studies is that damage to neural
systems paradoxically results in enhanced functional connectivity between network regions …