The noncanonical pathway for in vivo nitric oxide generation: the nitrate-nitrite-nitric oxide pathway

V Kapil, RS Khambata, DA Jones, K Rathod… - Pharmacological …, 2020 - ASPET
In contrast to nitric oxide, which has well established and important roles in the regulation of
blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary …

Recommendations for diagnosis and treatment of methemoglobinemia

A Iolascon, P Bianchi, I Andolfo… - American journal of …, 2021 - Wiley Online Library
Methemoglobinemia is a rare disorder associated with oxidization of divalent ferro‐iron of
hemoglobin (Hb) to ferri‐iron of methemoglobin (MetHb). Methemoglobinemia can result …

A multi-model study for understanding the contamination mechanisms, toxicity and health risks of hardness, sulfate, and nitrate in natural water resources

JC Egbueri - Environmental Science and Pollution Research, 2023 - Springer
Several water quality contaminants have attracted the attention of numerous researchers
globally, in recent times. Although the toxicity and health risk assessments of sulfate and …

Human health risks associated with multipath exposure of groundwater nitrate and environmental friendly actions for quality improvement and sustainable …

D Karunanidhi, P Aravinthasamy, T Subramani… - Chemosphere, 2021 - Elsevier
The present research was attempted to examine the human health risks due to nitrate
contamination in the groundwater of Texvalley (Tiruppur region) of southern India …

Fatal methemoglobinemia: a case series highlighting a new trend in intentional sodium nitrite or sodium nitrate ingestion as a method of suicide

TBM Hickey, JA MacNeil, C Hansmeyer… - Forensic science …, 2021 - Elsevier
Unintentional exposure to nitrite-or nitrate-containing toxic salts is a recognized cause of
acquired methemoglobinemia (MetHb). This systemic alteration of the blood can be fatal if …

Health risk assessment of groundwater nitrate contamination: a case study of a typical karst hydrogeological unit in East China

S Gao, C Li, C Jia, H Zhang, Q Guan, X Wu… - … Science and Pollution …, 2020 - Springer
Nitrate pollution in rivers, lakes, shallow groundwater, and even deep groundwater occurs in
many parts of the world. And, it's essential to assessing the relationship between nitrate …

Groundwater quality evolution based on geochemical modeling and aptness testing for ingestion using entropy water quality and total hazard indexes in an urban …

D Karunanidhi, P Aravinthasamy, M Deepali… - … Science and Pollution …, 2021 - Springer
This study used geochemical modeling to understand the chemical evolution of
groundwater, entropy water quality index to assess the aptness of groundwater for human …

[HTML][HTML] Methemoglobinemia

JT Ludlow, RG Wilkerson, TM Nappe - 2019 - europepmc.org
Objectives: Review the causes of methemoglobinemia. Describe the presentation of
methemoglobinemia. Explain the management of methemoglobinemia. Outline the …

Does the groundwater nitrate pollution in China pose a risk to human health? A critical review of published data

Y Zhai, Y Lei, J Wu, Y Teng, J Wang, X Zhao… - … Science and Pollution …, 2017 - Springer
Nitrate pollution has pervaded many parts of the world, especially in developing countries
such as China. Based on the available groundwater nitrate data sets in China (2000–2015) …

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Rasburicase Therapy in the Context of G6PD Deficiency Genotype

MV Relling, EM McDonagh, T Chang… - Clinical …, 2014 - Wiley Online Library
Glucose‐6‐phosphate dehydrogenase (G6PD) deficiency is associated with development of
acute hemolytic anemia (AHA) induced by a number of drugs. We provide guidance as to …