Therapeutic oxygen delivery by perfluorocarbon-based colloids

MP Krafft, JG Riess - Advances in colloid and interface science, 2021 - Elsevier
After the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/
phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed …

[HTML][HTML] Bubble nucleation and dynamics in acoustic droplet vaporization: a review of concepts, applications, and new directions

M Aliabouzar, OD Kripfgans, JB Fowlkes… - … für Medizinische Physik, 2023 - Elsevier
The development of phase-shift droplets has broadened the scope of ultrasound-based
biomedical applications. When subjected to sufficient acoustic pressures, the …

Ultrasonic cavitation‐assisted and acid‐activated transcytosis of liposomes for universal active tumor penetration

G Wang, C Zhang, Y Jiang, Y Song… - Advanced Functional …, 2021 - Wiley Online Library
Active tumor penetration has been recently recognized as a promising strategy to resolve
the limitation of nanomedicine in terms of tumor penetration, but it is challenging to develop …

Factors influencing the repeated transient optical droplet vaporization threshold and lifetimes of phase change, perfluorocarbon nanodroplets

AX Zhao, YI Zhu, E Chung, J Lee, S Morais, H Yoon… - Nanomaterials, 2023 - mdpi.com
Perfluorocarbon nanodroplets (PFCnDs) are sub-micrometer emulsions composed of a
surfactant-encased perfluorocarbon (PFC) liquid and can be formulated to transiently …

[HTML][HTML] Stable and transient bubble formation in acoustically-responsive scaffolds by acoustic droplet vaporization: theory and application in sequential release

M Aliabouzar, OD Kripfgans, WY Wang… - Ultrasonics …, 2021 - Elsevier
Abstract Acoustically-responsive scaffolds (ARSs), which are fibrin hydrogels containing
monodispersed perfluorocarbon (PFC) emulsions, respond to ultrasound in an on-demand …

Investigation of the acoustic vaporization threshold of lipid-coated perfluorobutane nanodroplets using both high-speed optical imaging and acoustic methods

Q Wu, C Mannaris, JP May, L Bau, A Polydorou… - Ultrasound in Medicine …, 2021 - Elsevier
A combination of ultrahigh-speed optical imaging (5× 10 6 frames/s), B-mode ultrasound
and passive cavitation detection was used to study the vaporization process and determine …

[HTML][HTML] Numerical investigation of acoustic vaporization threshold of microdroplets

S Park, G Son - Ultrasonics Sonochemistry, 2021 - Elsevier
A numerical model is presented for the acoustic vaporization threshold of a
dodecafluoropentane (or perfluoropentane) microdroplet. The model is based on the …

Acoustic nanodrops for biomedical applications

MA Borden, G Shakya, A Upadhyay… - Current opinion in colloid & …, 2020 - Elsevier
Acoustic nanodrops are designed to vaporize into ultrasound-responsive microbubbles,
which present certain challenges nonexistent for conventional nanoemulsions. The …

Repeated acoustic vaporization of perfluorohexane nanodroplets for contrast-enhanced ultrasound imaging

A Van Namen, S Jandhyala, T Jordan… - IEEE transactions on …, 2021 - ieeexplore.ieee.org
Superheated perfluorocarbon nanodroplets are emerging ultrasound imaging contrast
agents that boast biocompatible components, unique phase-change dynamics, and …

[HTML][HTML] Numerical study of the effect of liquid compressibility on acoustic droplet vaporization

S Park, G Son - Ultrasonics Sonochemistry, 2021 - Elsevier
In acoustic droplet vaporization (ADV), a cavitated bubble grows and collapses depending
on the pressure amplitude of the acoustic pulse. During the bubble collapse, the …